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Loss of SORCS2 is Associated with Neuronal DNA Double-Strand Breaks.
Gospodinova KO, Olsen D, Kaas M, Anderson SM, Phillips J, Walker RM, Bermingham ML, Payne AL, Giannopoulos P, Pandya D, Spires-Jones TL, Abbott CM, Porteous DJ, Glerup S, Evans KL. Gospodinova KO, et al. Cell Mol Neurobiol. 2023 Jan;43(1):237-249. doi: 10.1007/s10571-021-01163-7. Epub 2021 Nov 6. Cell Mol Neurobiol. 2023. PMID: 34741697 Free PMC article.
An epigenetic predictor of death captures multi-modal measures of brain health.
Hillary RF, Stevenson AJ, Cox SR, McCartney DL, Harris SE, Seeboth A, Higham J, Sproul D, Taylor AM, Redmond P, Corley J, Pattie A, Hernández MDCV, Muñoz-Maniega S, Bastin ME, Wardlaw JM, Horvath S, Ritchie CW, Spires-Jones TL, McIntosh AM, Evans KL, Deary IJ, Marioni RE. Hillary RF, et al. Mol Psychiatry. 2021 Aug;26(8):3806-3816. doi: 10.1038/s41380-019-0616-9. Epub 2019 Dec 3. Mol Psychiatry. 2021. PMID: 31796892 Free PMC article.
Creating and Validating a DNA Methylation-Based Proxy for Interleukin-6.
Stevenson AJ, Gadd DA, Hillary RF, McCartney DL, Campbell A, Walker RM, Evans KL, Harris SE, Spires-Jones TL, McRae AF, Visscher PM, McIntosh AM, Deary IJ, Marioni RE. Stevenson AJ, et al. J Gerontol A Biol Sci Med Sci. 2021 Nov 15;76(12):2284-2292. doi: 10.1093/gerona/glab046. J Gerontol A Biol Sci Med Sci. 2021. PMID: 33595649 Free PMC article.
Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis.
Petrozziello T, Bordt EA, Mills AN, Kim SE, Sapp E, Devlin BA, Obeng-Marnu AA, Farhan SMK, Amaral AC, Dujardin S, Dooley PM, Henstridge C, Oakley DH, Neueder A, Hyman BT, Spires-Jones TL, Bilbo SD, Vakili K, Cudkowicz ME, Berry JD, DiFiglia M, Silva MC, Haggarty SJ, Sadri-Vakili G. Petrozziello T, et al. Mol Neurobiol. 2022 Jan;59(1):683-702. doi: 10.1007/s12035-021-02557-w. Epub 2021 Nov 10. Mol Neurobiol. 2022. PMID: 34757590
Neurogranin in Alzheimer's disease and ageing: A human post-mortem study.
Saunders T, Gunn C, Blennow K, Kvartsberg H, Zetterberg H, Shenkin SD, Cox SR, Deary IJ, Smith C, King D, Spires-Jones T. Saunders T, et al. Neurobiol Dis. 2023 Feb;177:105991. doi: 10.1016/j.nbd.2023.105991. Epub 2023 Jan 6. Neurobiol Dis. 2023. PMID: 36623608 Free article.
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease.
Yeap J, Sathyaprakash C, Toombs J, Tulloch J, Scutariu C, Rose J, Burr K, Davies C, Colom-Cadena M, Chandran S, Large CH, Rowan MJM, Gunthorpe MJ, Spires-Jones TL. Yeap J, et al. Brain Neurosci Adv. 2022 Mar 24;6:23982128221086464. doi: 10.1177/23982128221086464. eCollection 2022 Jan-Dec. Brain Neurosci Adv. 2022. PMID: 35359460 Free PMC article.
173 results