Plach MG - Search Results

1

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions.

Brun S, Bestion E, Raymond E, Bassissi F, Jilkova ZM, Mezouar S, Rachid M, Novello M, Tracz J, Hamaï A, Lalmanach G, Vanderlynden L, Legouffe R, Stauber J, Schubert T, Plach MG, Courcambeck J, Drouot C, Jacquemot G, Serdjebi C, Roth G, Baudoin JP, Ansaldi C, Decaens T, Halfon P. Brun S, et al. Among authors: plach mg. Autophagy. 2022 Mar;18(3):678-694. doi: 10.1080/15548627.2021.1988357. Epub 2021 Nov 5. Autophagy. 2022. PMID: 34740311 Free PMC article.

2

Biophysical Characterization of Aptamer-Target Interactions.

Plach M, Schubert T. Plach M, et al. Adv Biochem Eng Biotechnol. 2020;174:1-15. doi: 10.1007/10_2019_103. Adv Biochem Eng Biotechnol. 2020. PMID: 31375847 Review.

3

MicroScale Thermophoresis as a Tool to Study Protein-peptide Interactions in the Context of Large Eukaryotic Protein Complexes.

Plach MG, Grasser K, Schubert T. Plach MG, et al. Bio Protoc. 2017 Dec 5;7(23):e2632. doi: 10.21769/BioProtoc.2632. eCollection 2017 Dec 5. Bio Protoc. 2017. PMID: 34595300 Free PMC article.

4

Evolutionary diversification of protein-protein interactions by interface add-ons.

Plach MG, Semmelmann F, Busch F, Busch M, Heizinger L, Wysocki VH, Merkl R, Sterner R. Plach MG, et al. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8333-E8342. doi: 10.1073/pnas.1707335114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923934 Free PMC article.

5

Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation.

Plach MG, Reisinger B, Sterner R, Merkl R. Plach MG, et al. PLoS Genet. 2016 Jan 29;12(1):e1005836. doi: 10.1371/journal.pgen.1005836. eCollection 2016 Jan. PLoS Genet. 2016. PMID: 26824644 Free PMC article.

6

Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism.

Veprinskiy V, Heizinger L, Plach MG, Merkl R. Veprinskiy V, et al. Among authors: plach mg. BMC Evol Biol. 2017 Jan 26;17(1):36. doi: 10.1186/s12862-017-0886-2. BMC Evol Biol. 2017. PMID: 28125959 Free PMC article.

7

Conversion of anthranilate synthase into isochorismate synthase: implications for the evolution of chorismate-utilizing enzymes.

Plach MG, Löffler P, Merkl R, Sterner R. Plach MG, et al. Angew Chem Int Ed Engl. 2015 Sep 14;54(38):11270-4. doi: 10.1002/anie.201505063. Angew Chem Int Ed Engl. 2015. PMID: 26352034

8

AGeNNT: annotation of enzyme families by means of refined neighborhood networks.

Kandlinger F, Plach MG, Merkl R. Kandlinger F, et al. Among authors: plach mg. BMC Bioinformatics. 2017 May 25;18(1):274. doi: 10.1186/s12859-017-1689-6. BMC Bioinformatics. 2017. PMID: 28545394 Free PMC article.

9

SEC-SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded-Over Conformations.

Smith KP, Chakravarthy S, Rahi A, Chakraborty M, Vosberg KM, Tonelli M, Plach MG, Grigorescu AA, Curtis JE, Varma D. Smith KP, et al. Among authors: plach mg. Cytoskeleton (Hoboken). 2024 Nov 6. doi: 10.1002/cm.21954. Online ahead of print. Cytoskeleton (Hoboken). 2024. PMID: 39503309

10

SAXS/MC studies of the mixed-folded protein Cdt1 reveal monomeric, folded over conformations.

Smith KP, Chakravarthy S, Rahi A, Chakraborty M, Vosberg KM, Tonelli M, Plach MG, Grigorescu AA, Curtis JE, Varma D. Smith KP, et al. Among authors: plach mg. bioRxiv [Preprint]. 2024 Jan 3:2024.01.03.573975. doi: 10.1101/2024.01.03.573975. bioRxiv. 2024. Update in: Cytoskeleton (Hoboken). 2024 Nov 6. doi: 10.1002/cm.21954 PMID: 38260441 Free PMC article. Updated. Preprint.

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