Newton AC - Search Results

1

Conventional protein kinase C in the brain: repurposing cancer drugs for neurodegenerative treatment?

Lordén G, Newton AC. Lordén G, et al. Among authors: newton ac. Neuronal Signal. 2021 Oct 8;5(4):NS20210036. doi: 10.1042/NS20210036. eCollection 2021 Dec. Neuronal Signal. 2021. PMID: 34737895 Free PMC article. Review.

2

Protein kinase C as a tumor suppressor.

Newton AC. Newton AC. Semin Cancer Biol. 2018 Feb;48:18-26. doi: 10.1016/j.semcancer.2017.04.017. Epub 2017 May 2. Semin Cancer Biol. 2018. PMID: 28476658 Free PMC article. Review.

3

Protein kinase C: perfectly balanced.

Newton AC. Newton AC. Crit Rev Biochem Mol Biol. 2018 Apr;53(2):208-230. doi: 10.1080/10409238.2018.1442408. Crit Rev Biochem Mol Biol. 2018. PMID: 29513138 Free PMC article. Review.

4

Protein kinase Cα gain-of-function variant in Alzheimer's disease displays enhanced catalysis by a mechanism that evades down-regulation.

Callender JA, Yang Y, Lordén G, Stephenson NL, Jones AC, Brognard J, Newton AC. Callender JA, et al. Among authors: newton ac. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5497-E5505. doi: 10.1073/pnas.1805046115. Epub 2018 May 29. Proc Natl Acad Sci U S A. 2018. PMID: 29844158 Free PMC article.

5

Activation of atypical protein kinase C by sphingosine 1-phosphate revealed by an aPKC-specific activity reporter.

Kajimoto T, Caliman AD, Tobias IS, Okada T, Pilo CA, Van AN, Andrew McCammon J, Nakamura SI, Newton AC. Kajimoto T, et al. Among authors: newton ac. Sci Signal. 2019 Jan 1;12(562):eaat6662. doi: 10.1126/scisignal.aat6662. Sci Signal. 2019. PMID: 30600259 Free PMC article.

6

PHLPP1 counter-regulates STAT1-mediated inflammatory signaling.

Cohen Katsenelson K, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. Cohen Katsenelson K, et al. Among authors: newton ac. Elife. 2019 Aug 13;8:e48609. doi: 10.7554/eLife.48609. Elife. 2019. PMID: 31408005 Free PMC article.

7

Conventional protein kinase C in the brain: 40 years later.

Callender JA, Newton AC. Callender JA, et al. Among authors: newton ac. Neuronal Signal. 2017 Apr 10;1(2):NS20160005. doi: 10.1042/NS20160005. eCollection 2017 Apr. Neuronal Signal. 2017. PMID: 32714576 Free PMC article. Review.

8

Hypothesis: Unifying model of domain architecture for conventional and novel protein kinase C isozymes.

Jones AC, Taylor SS, Newton AC, Kornev AP. Jones AC, et al. Among authors: newton ac. IUBMB Life. 2020 Dec;72(12):2584-2590. doi: 10.1002/iub.2401. Epub 2020 Nov 9. IUBMB Life. 2020. PMID: 33166426 Free PMC article.

9

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

Kawashima AT, Wong C, Lordén G, King CC, Lara-Gonzalez P, Desai A, Gingras AC, Newton AC. Kawashima AT, et al. Among authors: newton ac. Mol Cell Biol. 2021 Feb 23;41(3):e0033320. doi: 10.1128/MCB.00333-20. Epub 2021 Jan 4. Mol Cell Biol. 2021. PMID: 33397691 Free PMC article.

10

PHLPPing the balance: restoration of protein kinase C in cancer.

Tovell H, Newton AC. Tovell H, et al. Among authors: newton ac. Biochem J. 2021 Jan 29;478(2):341-355. doi: 10.1042/BCJ20190765. Biochem J. 2021. PMID: 33502516 Free PMC article. Review.

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