Chen ZS - Search Results

1

Discovery of the Triazolo[1,5-a]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance.

Wang S, Wang SQ, Teng QX, Lei ZN, Chen ZS, Chen XB, Liu HM, Yu B. Wang S, et al. Among authors: chen zs, chen xb. J Med Chem. 2021 Nov 11;64(21):16187-16204. doi: 10.1021/acs.jmedchem.1c01498. Epub 2021 Nov 1. J Med Chem. 2021. PMID: 34723530

2

Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid.

Singh S, Prasad NR, Chufan EE, Patel BA, Wang YJ, Chen ZS, Ambudkar SV, Talele TT. Singh S, et al. Among authors: chen zs. J Med Chem. 2014 May 22;57(10):4058-72. doi: 10.1021/jm401966m. Epub 2014 May 7. J Med Chem. 2014. PMID: 24773054 Free PMC article.

3

Novel hybrids of natural oridonin-bearing nitrogen mustards as potential anticancer drug candidates.

Xu S, Pei L, Wang C, Zhang YK, Li D, Yao H, Wu X, Chen ZS, Sun Y, Xu J. Xu S, et al. Among authors: chen zs. ACS Med Chem Lett. 2014 May 28;5(7):797-802. doi: 10.1021/ml500141f. eCollection 2014 Jul 10. ACS Med Chem Lett. 2014. PMID: 25050168 Free PMC article.

4

1,2,3-Triazole-Dithiocarbamate Hybrids, a Group of Novel Cell Active SIRT1 Inhibitors.

Zheng YC, Wang LZ, Zhao LJ, Zhao LJ, Zhan QN, Ma JL, Zhang B, Wang MM, Wang ZR, Li JF, Liu Y, Chen ZS, Shen DD, Liu XQ, Ren M, Lv WL, Zhao W, Duan YC, Liu HM. Zheng YC, et al. Among authors: chen zs. Cell Physiol Biochem. 2016;38(1):185-93. doi: 10.1159/000438620. Epub 2016 Jan 20. Cell Physiol Biochem. 2016. PMID: 26784898 Free article.

5

Probing the Anticancer Action of Oridonin with Fluorescent Analogues: Visualizing Subcellular Localization to Mitochondria.

Xu S, Luo S, Yao H, Cai H, Miao X, Wu F, Yang DH, Wu X, Xie W, Yao H, Chen ZS, Xu J. Xu S, et al. Among authors: chen zs. J Med Chem. 2016 May 26;59(10):5022-34. doi: 10.1021/acs.jmedchem.6b00408. Epub 2016 Apr 27. J Med Chem. 2016. PMID: 27089099

6

TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy.

Zheng YC, Yu B, Chen ZS, Liu Y, Liu HM. Zheng YC, et al. Among authors: chen zs. Epigenomics. 2016 May;8(5):651-66. doi: 10.2217/epi-2015-0002. Epub 2016 Apr 22. Epigenomics. 2016. PMID: 27102879 Review.

7

A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway.

Xu S, Yao H, Luo S, Zhang YK, Yang DH, Li D, Wang G, Hu M, Qiu Y, Wu X, Yao H, Xie W, Chen ZS, Xu J. Xu S, et al. Among authors: chen zs. J Med Chem. 2017 Feb 23;60(4):1449-1468. doi: 10.1021/acs.jmedchem.6b01652. Epub 2017 Feb 13. J Med Chem. 2017. PMID: 28165738

8

Design, synthesis and biological evaluation of benzamide and phenyltetrazole derivatives with amide and urea linkers as BCRP inhibitors.

Gujarati NA, Zeng L, Gupta P, Chen ZS, Korlipara VL. Gujarati NA, et al. Among authors: chen zs. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4698-4704. doi: 10.1016/j.bmcl.2017.09.009. Epub 2017 Sep 7. Bioorg Med Chem Lett. 2017. PMID: 28916341

9

Establishment and characterization of arsenic trioxide resistant KB/ATO cells.

Zhang YK, Dai C, Yuan CG, Wu HC, Xiao Z, Lei ZN, Yang DH, Le XC, Fu L, Chen ZS. Zhang YK, et al. Among authors: chen zs. Acta Pharm Sin B. 2017 Sep;7(5):564-570. doi: 10.1016/j.apsb.2017.04.001. Epub 2017 Apr 28. Acta Pharm Sin B. 2017. PMID: 28924550 Free PMC article.

10

Design, synthesis and biological evaluation of WZ4002 analogues as EGFR inhibitors.

Romu AA, Lei Z, Zhou B, Chen ZS, Korlipara V. Romu AA, et al. Among authors: chen zs. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4832-4837. doi: 10.1016/j.bmcl.2017.09.048. Epub 2017 Sep 25. Bioorg Med Chem Lett. 2017. PMID: 28974338

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