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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.
Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Carette JE, et al. Among authors: kuehne ai. Nature. 2011 Aug 24;477(7364):340-3. doi: 10.1038/nature10348. Nature. 2011. PMID: 21866103 Free PMC article.
A shared structural solution for neutralizing ebolaviruses.
Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO. Dias JM, et al. Among authors: kuehne ai. Nat Struct Mol Biol. 2011 Nov 20;18(12):1424-7. doi: 10.1038/nsmb.2150. Nat Struct Mol Biol. 2011. PMID: 22101933 Free PMC article.
Ebola virus entry requires the host-programmed recognition of an intracellular receptor.
Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. Miller EH, et al. Among authors: kuehne ai. EMBO J. 2012 Apr 18;31(8):1947-60. doi: 10.1038/emboj.2012.53. Epub 2012 Mar 6. EMBO J. 2012. PMID: 22395071 Free PMC article.
Venezuelan equine encephalitis virus replicon particle vaccine protects nonhuman primates from intramuscular and aerosol challenge with ebolavirus.
Herbert AS, Kuehne AI, Barth JF, Ortiz RA, Nichols DK, Zak SE, Stonier SW, Muhammad MA, Bakken RR, Prugar LI, Olinger GG, Groebner JL, Lee JS, Pratt WD, Custer M, Kamrud KI, Smith JF, Hart MK, Dye JM. Herbert AS, et al. Among authors: kuehne ai. J Virol. 2013 May;87(9):4952-64. doi: 10.1128/JVI.03361-12. Epub 2013 Feb 13. J Virol. 2013. PMID: 23408633 Free PMC article.
Persistent immune responses after Ebola virus infection.
Sobarzo A, Ochayon DE, Lutwama JJ, Balinandi S, Guttman O, Marks RS, Kuehne AI, Dye JM, Yavelsky V, Lewis EC, Lobel L. Sobarzo A, et al. Among authors: kuehne ai. N Engl J Med. 2013 Aug 1;369(5):492-3. doi: 10.1056/NEJMc1300266. N Engl J Med. 2013. PMID: 23902512 Free article. No abstract available.
48 results