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The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations.
da Rocha JEB, Othman H, Botha G, Cottino L, Twesigomwe D, Ahmed S, Drögemöller BI, Fadlelmola FM, Machanick P, Mbiyavanga M, Panji S, Wright GEB, Adebamowo C, Matshaba M, Ramsay M, Simo G, Simuunza MC, Tiemessen CT, Baldwin S, Chiano M, Cox C, Gross AS, Thomas P, Gamo FJ, Hazelhurst S. da Rocha JEB, et al. Among authors: tiemessen ct. Front Pharmacol. 2021 Apr 28;12:634016. doi: 10.3389/fphar.2021.634016. eCollection 2021. Front Pharmacol. 2021. PMID: 34721006 Free PMC article.
Africa: the next frontier for human disease gene discovery?
Ramsay M, Tiemessen CT, Choudhury A, Soodyall H. Ramsay M, et al. Among authors: tiemessen ct. Hum Mol Genet. 2011 Oct 15;20(R2):R214-20. doi: 10.1093/hmg/ddr401. Epub 2011 Sep 9. Hum Mol Genet. 2011. PMID: 21908518 Review.
G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19.
da Rocha J, Othman H, Tiemessen CT, Botha G, Ramsay M, Masimirembwa C, Adebamowo C, Choudhury A, Brandenburg JT, Matshaba M, Simo G, Gamo FJ, Hazelhurst S; H3Africa Consortium. da Rocha J, et al. Among authors: tiemessen ct. medRxiv [Preprint]. 2020 Jun 2:2020.05.27.20114066. doi: 10.1101/2020.05.27.20114066. medRxiv. 2020. Update in: Pharmacogenomics J. 2021 Dec;21(6):649-656. doi: 10.1038/s41397-021-00242-8 PMID: 32577690 Free PMC article. Updated. Preprint.
G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19.
da Rocha JEB, Othman H, Tiemessen CT, Botha G, Ramsay M, Masimirembwa C, Adebamowo C, Choudhury A, Brandenburg JT, Matshaba M, Simo G, Gamo FJ, Hazelhurst S; as members of the H3Africa Consortium. da Rocha JEB, et al. Among authors: tiemessen ct. Pharmacogenomics J. 2021 Dec;21(6):649-656. doi: 10.1038/s41397-021-00242-8. Epub 2021 Jul 23. Pharmacogenomics J. 2021. PMID: 34302047 Free PMC article.
Characterization of CYP2D6 Pharmacogenetic Variation in Sub-Saharan African Populations.
Twesigomwe D, Drögemöller BI, Wright GEB, Adebamowo C, Agongo G, Boua PR, Matshaba M, Paximadis M, Ramsay M, Simo G, Simuunza MC, Tiemessen CT, Lombard Z, Hazelhurst S. Twesigomwe D, et al. Among authors: tiemessen ct. Clin Pharmacol Ther. 2023 Mar;113(3):643-659. doi: 10.1002/cpt.2749. Epub 2022 Oct 21. Clin Pharmacol Ther. 2023. PMID: 36111505 Free PMC article.
An assessment of the genomic structural variation landscape in Sub-Saharan African populations.
Wiener E, Cottino L, Botha G, Nyangiri O, Noyes H, McLeod A, Jakubosky D, Adebamowo C, Awadalla P, Landouré G, Matshaba M, Matovu E, Ramsay M, Simo G, Simuunza M, Tiemessen C, Wonkam A, Sahibdeen V, Krause A, Lombard Z, Hazelhurst S; as members of the H3Africa Consortium. Wiener E, et al. Res Sq [Preprint]. 2024 Jul 8:rs.3.rs-4485126. doi: 10.21203/rs.3.rs-4485126/v1. Res Sq. 2024. PMID: 39041024 Free PMC article. Preprint.
178 results