Xu J - Search Results

1

High throughput screening data for a case study of CHO cell culture process development.

He Q, Xu J, Vandermark E, Tian J, Qian Y, Chelius C, Lee J, Borys MC, Li ZJ, Pendse G. He Q, et al. Among authors: xu j. Data Brief. 2021 Oct 17;39:107491. doi: 10.1016/j.dib.2021.107491. eCollection 2021 Dec. Data Brief. 2021. PMID: 34712760 Free PMC article.

2

Galactose can be an inducer for production of therapeutic proteins by auto-induction using E. coli BL21 strains.

Xu J, Banerjee A, Pan SH, Li ZJ. Xu J, et al. Protein Expr Purif. 2012 May;83(1):30-6. doi: 10.1016/j.pep.2012.02.014. Epub 2012 Mar 8. Protein Expr Purif. 2012. PMID: 22425658

3

Reduction of N-terminal methionylation while increasing titer by lowering metabolic and protein production rates in E. coli auto-induced fed-batch fermentation.

Xu J, Qian Y, Skonezny PM, You L, Xing Z, Meyers DS, Stankavage RJ, Pan SH, Li ZJ. Xu J, et al. J Ind Microbiol Biotechnol. 2012 Aug;39(8):1199-208. doi: 10.1007/s10295-012-1127-8. Epub 2012 Apr 20. J Ind Microbiol Biotechnol. 2012. PMID: 22526331

4

A mechanistic kinetic description of lactate dehydrogenase elucidating cancer diagnosis and inhibitor evaluation.

Tang P, Xu J, Oliveira CL, Li ZJ, Liu S. Tang P, et al. Among authors: xu j. J Enzyme Inhib Med Chem. 2017 Dec;32(1):564-571. doi: 10.1080/14756366.2016.1275606. J Enzyme Inhib Med Chem. 2017. PMID: 28114833 Free PMC article.

5

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media.

Xu J, Rehmann MS, Xu X, Huang C, Tian J, Qian NX, Li ZJ. Xu J, et al. Among authors: xu x. MAbs. 2018 Apr;10(3):488-499. doi: 10.1080/19420862.2018.1433978. Epub 2018 Feb 20. MAbs. 2018. PMID: 29388872 Free PMC article.

6

Systematic development of temperature shift strategies for Chinese hamster ovary cells based on short duration cultures and kinetic modeling.

Xu J, Tang P, Yongky A, Drew B, Borys MC, Liu S, Li ZJ. Xu J, et al. MAbs. 2019 Jan;11(1):191-204. doi: 10.1080/19420862.2018.1525262. Epub 2018 Oct 2. MAbs. 2019. PMID: 30230966 Free PMC article.

7

Process intensification in fed-batch production bioreactors using non-perfusion seed cultures.

Yongky A, Xu J, Tian J, Oliveira C, Zhao J, McFarland K, Borys MC, Li ZJ. Yongky A, et al. Among authors: xu j. MAbs. 2019 Nov-Dec;11(8):1502-1514. doi: 10.1080/19420862.2019.1652075. Epub 2019 Aug 19. MAbs. 2019. PMID: 31379298 Free PMC article.

8

Kinetic modeling of Chinese hamster ovary cell culture: factors and principles.

Tang P, Xu J, Louey A, Tan Z, Yongky A, Liang S, Li ZJ, Weng Y, Liu S. Tang P, et al. Among authors: xu j. Crit Rev Biotechnol. 2020 Mar;40(2):265-281. doi: 10.1080/07388551.2019.1711015. Epub 2020 Jan 12. Crit Rev Biotechnol. 2020. PMID: 31928250

9

Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells.

McHugh KP, Xu J, Aron KL, Borys MC, Li ZJ. McHugh KP, et al. Among authors: xu j. Biotechnol Prog. 2020 May;36(3):e2959. doi: 10.1002/btpr.2959. Epub 2020 Jan 17. Biotechnol Prog. 2020. PMID: 31930722

10

Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study.

Xu J, Xu X, Huang C, Angelo J, Oliveira CL, Xu M, Xu X, Temel D, Ding J, Ghose S, Borys MC, Li ZJ. Xu J, et al. Among authors: xu m, xu x. MAbs. 2020 Jan 1;12(1):1770669. doi: 10.1080/19420862.2020.1770669. MAbs. 2020. PMID: 32425110 Free PMC article.

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