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Bone marrow osteoprogenitors are depleted whereas osteoblasts are expanded independent of the osteogenic vasculature in response to zoledronic acid.
Hughes R, Chen X, Hunter KD, Hobbs JK, Holen I, Brown NJ. Hughes R, et al. Among authors: chen x. FASEB J. 2019 Nov;33(11):12768-12779. doi: 10.1096/fj.201900553RR. Epub 2019 Sep 6. FASEB J. 2019. PMID: 31490705 Free PMC article.
Collectively, our data demonstrate that ZOL affects multiple cell types in bone and has differential effects depending on the level of bone turnover.-Hughes, R., Chen, X., Hunter, K. D., Hobbs, J. K., Holen, I., Brown, N. J. Bone marrow osteoprogenitors are depleted …
Collectively, our data demonstrate that ZOL affects multiple cell types in bone and has differential effects depending on the level of bone …
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