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Page 1
Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas.
Lehman NL, O'Donnell JP, Whiteley LJ, Stapp RT, Lehman TD, Roszka KM, Schultz LR, Williams CJ, Mikkelsen T, Brown SL, Ecsedy JA, Poisson LM. Lehman NL, et al. Among authors: lehman td. Cell Cycle. 2012 Feb 1;11(3):489-502. doi: 10.4161/cc.11.3.18996. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22274399 Free PMC article.
Differential expression of aurora-A kinase in T-cell lymphomas.
Kanagal-Shamanna R, Lehman NL, O'Donnell JP, Lim MS, Schultz DS, Chitale DA, Bueso-Ramos CE, Medeiros LJ, Inamdar KV. Kanagal-Shamanna R, et al. Among authors: lehman nl. Mod Pathol. 2013 May;26(5):640-7. doi: 10.1038/modpathol.2012.211. Epub 2013 Feb 15. Mod Pathol. 2013. PMID: 23411487 Free PMC article.
The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation.
Hong X, O'Donnell JP, Salazar CR, Van Brocklyn JR, Barnett KD, Pearl DK, deCarvalho AC, Ecsedy JA, Brown SL, Mikkelsen T, Lehman NL. Hong X, et al. Among authors: lehman nl. Cancer Chemother Pharmacol. 2014 May;73(5):983-90. doi: 10.1007/s00280-014-2430-z. Epub 2014 Mar 14. Cancer Chemother Pharmacol. 2014. PMID: 24627220 Free PMC article.
Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells.
Sak M, Zumbar CT, King PD, Li X, Mifsud CS, Usubalieva A, Anderson CD, Chesnick HM, McElroy JP, Chakravarti A, Burton EC, Lehman NL. Sak M, et al. Among authors: lehman nl. J Neurooncol. 2019 Jun;143(2):231-240. doi: 10.1007/s11060-019-03164-5. Epub 2019 Apr 22. J Neurooncol. 2019. PMID: 31011934 Free PMC article.
Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
Lehman NL, Spassky N, Sak M, Webb A, Zumbar CT, Usubalieva A, Alkhateeb KJ, McElroy JP, Maclean KH, Fadda P, Liu T, Gangalapudi V, Carver J, Abdullaev Z, Timmers C, Parker JR, Pierson CR, Mobley BC, Gokden M, Hattab EM, Parrett T, Cooke RX, Lehman TD, Costinean S, Parwani A, Williams BJ, Jensen RL, Aldape K, Mistry AM. Lehman NL, et al. Nat Commun. 2022 Apr 19;13(1):2083. doi: 10.1038/s41467-022-29302-8. Nat Commun. 2022. PMID: 35440587 Free PMC article.
Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
Lehman NL, Spassky N, Sak M, Webb A, Zumbar CT, Usubalieva A, Alkhateeb KJ, McElroy JP, Maclean KH, Fadda P, Liu T, Gangalapudi V, Carver J, Abdullaev Z, Timmers C, Parker JR, Pierson CR, Mobley BC, Gokden M, Hattab EM, Parrett T, Cooke RX, Lehman TD, Costinean S, Parwani A, Williams BJ, Jensen RL, Aldape K, Mistry AM. Lehman NL, et al. Nat Commun. 2023 Jan 31;14(1):507. doi: 10.1038/s41467-023-36255-z. Nat Commun. 2023. PMID: 36720866 Free PMC article. No abstract available.
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