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Page 1
Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types.
Umar S, Palasiewicz K, Volin MV, Romay B, Rahat R, Tetali C, Arami S, Guma M, Ascoli C, Sweiss N, Zomorrodi RK, O'Neill LAJ, Shahrara S. Umar S, et al. Among authors: zomorrodi rk. Cell Mol Life Sci. 2021 Dec;78(23):7693-7707. doi: 10.1007/s00018-021-03978-5. Epub 2021 Oct 27. Cell Mol Life Sci. 2021. PMID: 34705053 Free PMC article.
Macrophages are the primary effector cells in IL-7-induced arthritis.
Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S. Kim SJ, et al. Among authors: zomorrodi rk. Cell Mol Immunol. 2020 Jul;17(7):728-740. doi: 10.1038/s41423-019-0235-z. Epub 2019 Jun 13. Cell Mol Immunol. 2020. PMID: 31197255 Free PMC article.
IRAK4 inhibition: a promising strategy for treating RA joint inflammation and bone erosion.
Umar S, Palasiewicz K, Van Raemdonck K, Volin MV, Romay B, Amin MA, Zomorrodi RK, Arami S, Gonzalez M, Rao V, Zanotti B, Fox DA, Sweiss N, Shahrara S. Umar S, et al. Among authors: zomorrodi rk. Cell Mol Immunol. 2021 Sep;18(9):2199-2210. doi: 10.1038/s41423-020-0433-8. Epub 2020 May 15. Cell Mol Immunol. 2021. PMID: 32415262 Free PMC article.
Interleukin-34 Reprograms Glycolytic and Osteoclastic Rheumatoid Arthritis Macrophages via Syndecan 1 and Macrophage Colony-Stimulating Factor Receptor.
Van Raemdonck K, Umar S, Palasiewicz K, Volin MV, Elshabrawy HA, Romay B, Tetali C, Ahmed A, Amin MA, Zomorrodi RK, Sweiss N, Shahrara S. Van Raemdonck K, et al. Among authors: zomorrodi rk. Arthritis Rheumatol. 2021 Nov;73(11):2003-2014. doi: 10.1002/art.41792. Epub 2021 Sep 22. Arthritis Rheumatol. 2021. PMID: 33982895 Free PMC article.
Metabolic reprogramming of macrophages instigates CCL21-induced arthritis.
Van Raemdonck K, Umar S, Palasiewicz K, Meyer A, Volin MV, Chang HJ, Al-Awqati M, Zomorrodi RK, Shahrara S. Van Raemdonck K, et al. Among authors: zomorrodi rk. Immunol Cell Biol. 2022 Feb;100(2):127-135. doi: 10.1111/imcb.12512. Epub 2021 Dec 6. Immunol Cell Biol. 2022. PMID: 34779007 Free PMC article.