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Page 1
TRPC6, a therapeutic target for pulmonary hypertension.
Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Jain PP, et al. Among authors: shyy jy. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321(6):L1161-L1182. doi: 10.1152/ajplung.00159.2021. Epub 2021 Oct 27. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34704831 Free PMC article.
AMP-activated Protein Kinase Phosphorylation of Angiotensin-Converting Enzyme 2 in Endothelium Mitigates Pulmonary Hypertension.
Zhang J, Dong J, Martin M, He M, Gongol B, Marin TL, Chen L, Shi X, Yin Y, Shang F, Wu Y, Huang HY, Zhang J, Zhang Y, Kang J, Moya EA, Huang HD, Powell FL, Chen Z, Thistlethwaite PA, Yuan ZY, Shyy JY. Zhang J, et al. Among authors: shyy jy. Am J Respir Crit Care Med. 2018 Aug 15;198(4):509-520. doi: 10.1164/rccm.201712-2570OC. Am J Respir Crit Care Med. 2018. PMID: 29570986 Free PMC article.
MicroRNA-483 amelioration of experimental pulmonary hypertension.
Zhang J, He Y, Yan X, Chen S, He M, Lei Y, Zhang J, Gongol B, Gu M, Miao Y, Bai L, Cui X, Wang X, Zhang Y, Fan F, Li Z, Shen Y, Chou CH, Huang HD, Malhotra A, Rabinovitch M, Jing ZC, Shyy JY. Zhang J, et al. Among authors: shyy jy. EMBO Mol Med. 2020 May 8;12(5):e11303. doi: 10.15252/emmm.201911303. Epub 2020 Apr 23. EMBO Mol Med. 2020. PMID: 32324970 Free PMC article.
MDM2-Mediated Ubiquitination of Angiotensin-Converting Enzyme 2 Contributes to the Development of Pulmonary Arterial Hypertension.
Shen H, Zhang J, Wang C, Jain PP, Xiong M, Shi X, Lei Y, Chen S, Yin Q, Thistlethwaite PA, Wang J, Gong K, Yuan ZY, Yuan JX, Shyy JY. Shen H, et al. Among authors: shyy jy. Circulation. 2020 Sep 22;142(12):1190-1204. doi: 10.1161/CIRCULATIONAHA.120.048191. Epub 2020 Jul 28. Circulation. 2020. PMID: 32755395 Free PMC article.
Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung.
Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Yuan JX. Jain PP, et al. Among authors: shyy jy. Pulm Circ. 2020 Nov 25;10(4):2045894020956592. doi: 10.1177/2045894020956592. eCollection 2020 Oct-Dec. Pulm Circ. 2020. PMID: 33282184 Free PMC article.
Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension.
Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. Wu K, et al. Among authors: shyy jy. Pulm Circ. 2020 Sep 10;10(3):2045894020948470. doi: 10.1177/2045894020948470. eCollection 2020 Jul-Sep. Pulm Circ. 2020. PMID: 33294172 Free PMC article.
Halofuginone, a promising drug for treatment of pulmonary hypertension.
Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. Jain PP, et al. Among authors: shyy jy. Br J Pharmacol. 2021 Sep;178(17):3373-3394. doi: 10.1111/bph.15442. Epub 2021 Jul 31. Br J Pharmacol. 2021. PMID: 33694155 Free PMC article.
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2.
Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY. Lei Y, et al. Among authors: shyy jy. Circ Res. 2021 Apr 30;128(9):1323-1326. doi: 10.1161/CIRCRESAHA.121.318902. Epub 2021 Mar 31. Circ Res. 2021. PMID: 33784827 Free PMC article. No abstract available.
Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells.
Rodriguez M, Chen J, Jain PP, Babicheva A, Xiong M, Li J, Lai N, Zhao T, Hernandez M, Balistrieri A, Parmisano S, Simonson T, Breen E, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Rodriguez M, et al. Among authors: shyy jy. Front Physiol. 2021 Aug 2;12:714785. doi: 10.3389/fphys.2021.714785. eCollection 2021. Front Physiol. 2021. PMID: 34408668 Free PMC article.
164 results