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Oleanolic acid blocks the purine salvage pathway for cancer therapy by inactivating SOD1 and stimulating lysosomal proteolysis.
Liu D, Jin X, Yu G, Wang M, Liu L, Zhang W, Wu J, Wang F, Yang J, Luo Q, Cai L, Yang X, Ke X, Qu Y, Xu Z, Jia L, Chen WL. Liu D, et al. Among authors: yang x, yang j. Mol Ther Oncolytics. 2021 Aug 28;23:107-123. doi: 10.1016/j.omto.2021.08.013. eCollection 2021 Dec 17. Mol Ther Oncolytics. 2021. PMID: 34703880 Free PMC article.
Five-day water-only fasting decreased metabolic-syndrome risk factors and increased anti-aging biomarkers without toxicity in a clinical trial of normal-weight individuals.
Jiang Y, Yang X, Dong C, Lu Y, Yin H, Xiao B, Yang X, Chen W, Cheng W, Tian H, Guo L, Hu X, Fang H, Chen W, Li Z, Zhou W, Sun W, Guo X, Li S, Lin Y, He R, Chen X, Liu D, Zhang M, Zhang Y, Zhao H, Zheng P, Seyfried TN, Hoffman RM, Jia W, Ji G, Jia L. Jiang Y, et al. Among authors: yang x. Clin Transl Med. 2021 Aug;11(8):e502. doi: 10.1002/ctm2.502. Clin Transl Med. 2021. PMID: 34459130 Free PMC article. No abstract available.
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