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Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells.
Saito T, Chiba T, Yuki K, Zen Y, Oshima M, Koide S, Motoyama T, Ogasawara S, Suzuki E, Ooka Y, Tawada A, Tada M, Kanai F, Takiguchi Y, Iwama A, Yokosuka O. Saito T, et al. Among authors: koide s. PLoS One. 2013 Jul 29;8(7):e70010. doi: 10.1371/journal.pone.0070010. Print 2013. PLoS One. 2013. PMID: 23922888 Free PMC article.
The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells.
Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T, Yamazaki S, Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A. Miyagi S, et al. Among authors: koide s. Stem Cell Reports. 2014 Jan 23;2(2):145-52. doi: 10.1016/j.stemcr.2013.12.008. eCollection 2014 Feb 11. Stem Cell Reports. 2014. PMID: 24527388 Free PMC article.
Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development.
Mishima Y, Wang C, Miyagi S, Saraya A, Hosokawa H, Mochizuki-Kashio M, Nakajima-Takagi Y, Koide S, Negishi M, Sashida G, Naito T, Ishikura T, Onodera A, Nakayama T, Tenen DG, Yamaguchi N, Koseki H, Taniuchi I, Iwama A. Mishima Y, et al. Among authors: koide s. Nat Commun. 2014 Dec 18;5:5872. doi: 10.1038/ncomms6872. Nat Commun. 2014. PMID: 25519988 Free PMC article.
Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes.
Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-Takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, Nakauchi H, Suda T, Shinkai Y, Iwama A. Koide S, et al. Blood. 2016 Aug 4;128(5):638-49. doi: 10.1182/blood-2016-01-694810. Epub 2016 Jun 14. Blood. 2016. PMID: 27301860 Free article.
Dual Inhibition of EZH2 and EZH1 Sensitizes PRC2-Dependent Tumors to Proteasome Inhibition.
Rizq O, Mimura N, Oshima M, Saraya A, Koide S, Kato Y, Aoyama K, Nakajima-Takagi Y, Wang C, Chiba T, Ma A, Jin J, Iseki T, Nakaseko C, Iwama A. Rizq O, et al. Among authors: koide s. Clin Cancer Res. 2017 Aug 15;23(16):4817-4830. doi: 10.1158/1078-0432.CCR-16-2735. Epub 2017 May 10. Clin Cancer Res. 2017. PMID: 28490465 Free PMC article.
863 results