Austin CA - Search Results

1

Mechanisms to Repair Stalled Topoisomerase II-DNA Covalent Complexes.

Swan RL, Cowell IG, Austin CA. Swan RL, et al. Among authors: austin ca. Mol Pharmacol. 2022 Jan;101(1):24-32. doi: 10.1124/molpharm.121.000374. Epub 2021 Oct 23. Mol Pharmacol. 2022. PMID: 34689119 Review.

2

Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms alpha and beta.

Marsh KL, Willmore E, Tinelli S, Cornarotti M, Meczes EL, Capranico G, Fisher LM, Austin CA. Marsh KL, et al. Among authors: austin ca. Biochem Pharmacol. 1996 Dec 13;52(11):1675-85. doi: 10.1016/s0006-2952(96)00516-3. Biochem Pharmacol. 1996. PMID: 8986129

3

Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2 beta construct allows the study of topoisomerase II beta inhibitors in yeast.

Meczes EL, Marsh KL, Fisher LM, Rogers MP, Austin CA. Meczes EL, et al. Among authors: austin ca. Cancer Chemother Pharmacol. 1997;39(4):367-75. doi: 10.1007/s002800050585. Cancer Chemother Pharmacol. 1997. PMID: 9025779

4

Self-association of chromo domain peptides.

Cowell IG, Austin CA. Cowell IG, et al. Among authors: austin ca. Biochim Biophys Acta. 1997 Feb 8;1337(2):198-206. doi: 10.1016/s0167-4838(96)00165-3. Biochim Biophys Acta. 1997. PMID: 9048896

5

Eukaryotic DNA topoisomerase II beta.

Austin CA, Marsh KL. Austin CA, et al. Bioessays. 1998 Mar;20(3):215-26. doi: 10.1002/(SICI)1521-1878(199803)20:3<215::AID-BIES5>3.0.CO;2-Q. Bioessays. 1998. PMID: 9631649 Review.

6

Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique.

Willmore E, Frank AJ, Padget K, Tilby MJ, Austin CA. Willmore E, et al. Among authors: austin ca. Mol Pharmacol. 1998 Jul;54(1):78-85. doi: 10.1124/mol.54.1.78. Mol Pharmacol. 1998. PMID: 9658192

7

Nuclear distribution of human DNA topoisomerase IIbeta: a nuclear targeting signal resides in the 116-residue C-terminal tail.

Cowell IG, Willmore E, Chalton D, Marsh KL, Jazrawi E, Fisher LM, Austin CA. Cowell IG, et al. Among authors: austin ca. Exp Cell Res. 1998 Sep 15;243(2):232-40. doi: 10.1006/excr.1998.4150. Exp Cell Res. 1998. PMID: 9743583

8

Murine transgenic cells lacking DNA topoisomerase IIbeta are resistant to acridines and mitoxantrone: analysis of cytotoxicity and cleavable complex formation.

Errington F, Willmore E, Tilby MJ, Li L, Li G, Li W, Baguley BC, Austin CA. Errington F, et al. Among authors: austin ca. Mol Pharmacol. 1999 Dec;56(6):1309-16. doi: 10.1124/mol.56.6.1309. Mol Pharmacol. 1999. PMID: 10570059

9

Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53.

Cowell IG, Okorokov AL, Cutts SA, Padget K, Bell M, Milner J, Austin CA. Cowell IG, et al. Among authors: austin ca. Exp Cell Res. 2000 Feb 25;255(1):86-94. doi: 10.1006/excr.1999.4772. Exp Cell Res. 2000. PMID: 10666337

10

Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining).

Padget K, Carr R, Pearson AD, Tilby MJ, Austin CA. Padget K, et al. Among authors: austin ca. Biochem Pharmacol. 2000 Mar 15;59(6):629-38. doi: 10.1016/s0006-2952(99)00372-x. Biochem Pharmacol. 2000. PMID: 10677579

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