Dodhiawala P - Search Results

1

Phospho-Ser⁷⁸⁴-VCP Drives Resistance of Pancreatic Ductal Adenocarcinoma to Genotoxic Chemotherapies and Predicts the Chemo-Sensitizing Effect of VCP Inhibitor.

Wang F, Vij K, Li L, Dodhiawala P, Lim KH, Shao J. Wang F, et al. Among authors: dodhiawala p. Cancers (Basel). 2021 Oct 11;13(20):5076. doi: 10.3390/cancers13205076. Cancers (Basel). 2021. PMID: 34680224 Free PMC article.

2

Deciphering the Role of Innate Immune NF-ĸB Pathway in Pancreatic Cancer.

Khurana N, Dodhiawala PB, Bulle A, Lim KH. Khurana N, et al. Cancers (Basel). 2020 Sep 19;12(9):2675. doi: 10.3390/cancers12092675. Cancers (Basel). 2020. PMID: 32961746 Free PMC article. Review.

3

Oncogenic KRAS-Induced Feedback Inflammatory Signaling in Pancreatic Cancer: An Overview and New Therapeutic Opportunities.

Bansod S, Dodhiawala PB, Lim KH. Bansod S, et al. Among authors: dodhiawala pb. Cancers (Basel). 2021 Oct 31;13(21):5481. doi: 10.3390/cancers13215481. Cancers (Basel). 2021. PMID: 34771644 Free PMC article. Review.

4

The MK2/Hsp27 axis is a major survival mechanism for pancreatic ductal adenocarcinoma under genotoxic stress.

Grierson PM, Dodhiawala PB, Cheng Y, Chen TH, Khawar IA, Wei Q, Zhang D, Li L, Herndon J, Monahan JB, Ruzinova MB, Lim KH. Grierson PM, et al. Among authors: dodhiawala pb. Sci Transl Med. 2021 Dec;13(622):eabb5445. doi: 10.1126/scitranslmed.abb5445. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851698 Free PMC article.

5

IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma.

Somani VK, Zhang D, Dodhiawala PB, Lander VE, Liu X, Kang LI, Chen HP, Knolhoff BL, Li L, Grierson PM, Ruzinova MB, DeNardo DG, Lim KH. Somani VK, et al. Among authors: dodhiawala pb. Gastroenterology. 2022 Jun;162(7):2047-2062. doi: 10.1053/j.gastro.2022.02.035. Epub 2022 Mar 7. Gastroenterology. 2022. PMID: 35271824 Free PMC article.

6

TPL2 enforces RAS-induced inflammatory signaling and is activated by point mutations.

Dodhiawala PB, Khurana N, Zhang D, Cheng Y, Li L, Wei Q, Seehra K, Jiang H, Grierson PM, Wang-Gillam A, Lim KH. Dodhiawala PB, et al. J Clin Invest. 2020 Sep 1;130(9):4771-4790. doi: 10.1172/JCI137660. J Clin Invest. 2020. PMID: 32573499 Free PMC article.

7

Concurrent HER or PI3K Inhibition Potentiates the Antitumor Effect of the ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models.

Jiang H, Xu M, Li L, Grierson P, Dodhiawala P, Highkin M, Zhang D, Li Q, Wang-Gillam A, Lim KH. Jiang H, et al. Among authors: dodhiawala p. Mol Cancer Ther. 2018 Oct;17(10):2144-2155. doi: 10.1158/1535-7163.MCT-17-1142. Epub 2018 Jul 31. Mol Cancer Ther. 2018. PMID: 30065098 Free PMC article.

8

Nitrogen Starvation-induced Phosphorylation of Ras1 Protein and Its Potential Role in Nutrient Signaling and Stress Response.

Jin X, Starke S, Li Y, Sethupathi S, Kung G, Dodhiawala P, Wang Y. Jin X, et al. Among authors: dodhiawala p. J Biol Chem. 2016 Jul 29;291(31):16231-9. doi: 10.1074/jbc.M115.713206. Epub 2016 Jun 3. J Biol Chem. 2016. PMID: 27261458 Free PMC article.

9

The TRIM4 E3 ubiquitin ligase degrades TPL2 and is modulated by oncogenic KRAS.

Bansod S, Dodhiawala PB, Geng Y, Bulle A, Liu P, Li L, Townsend R, Grierson PM, Held JM, Adhikari H, Lim KH. Bansod S, et al. Among authors: dodhiawala pb. Cell Rep. 2024 Sep 24;43(9):114667. doi: 10.1016/j.celrep.2024.114667. Epub 2024 Aug 22. Cell Rep. 2024. PMID: 39178114 Free PMC article.

10

Striking a balance: the Goldilocks effect of CD8α expression on NK cells.

Dodhiawala PB, Cichocki F. Dodhiawala PB, et al. J Clin Invest. 2024 Aug 1;134(15):e182905. doi: 10.1172/JCI182905. J Clin Invest. 2024. PMID: 39087476 Free PMC article.

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