Geibel C - Search Results

1

DoE Optimization Empowers the Automated Preparation of Enantiomerically Pure [¹⁸F]Talazoparib and its In Vivo Evaluation as a PARP Radiotracer.

Bowden GD, Stotz S, Kinzler J, Geibel C, Lämmerhofer M, Pichler BJ, Maurer A. Bowden GD, et al. Among authors: geibel c. J Med Chem. 2021 Nov 11;64(21):15690-15701. doi: 10.1021/acs.jmedchem.1c00903. Epub 2021 Oct 21. J Med Chem. 2021. PMID: 34672571

2

Evaluation of superficially porous particle based zwitterionic chiral ion exchangers against fully porous particle benchmarks for enantioselective ultra-high performance liquid chromatography.

Geibel C, Dittrich K, Woiwode U, Kohout M, Zhang T, Lindner W, Lämmerhofer M. Geibel C, et al. J Chromatogr A. 2019 Oct 11;1603:130-140. doi: 10.1016/j.chroma.2019.06.026. Epub 2019 Jun 14. J Chromatogr A. 2019. PMID: 31235330

3

Thiol-ene photo-click immobilization of a chiral chromatographic ligand on silica particles.

Geibel C, Dittrich K, Wolter M, Lämmerhofer M. Geibel C, et al. J Chromatogr A. 2020 Jul 5;1622:461133. doi: 10.1016/j.chroma.2020.461133. Epub 2020 Apr 19. J Chromatogr A. 2020. PMID: 32354557

4

Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability.

Andreev S, Pantsar T, El-Gokha A, Ansideri F, Kudolo M, Anton DB, Sita G, Romasco J, Geibel C, Lämmerhofer M, Goettert MI, Tarozzi A, Laufer SA, Koch P. Andreev S, et al. Among authors: geibel c. Int J Mol Sci. 2020 Oct 22;21(21):7823. doi: 10.3390/ijms21217823. Int J Mol Sci. 2020. PMID: 33105671 Free PMC article.

5

Preparation and characterization of poly(3-mercaptopropyl)methylsiloxane functionalized silica particles and their further modification for silver ion chromatography and enantioselective high-performance liquid chromatography.

Wolter M, Chen X, Woiwode U, Geibel C, Lämmerhofer M. Wolter M, et al. Among authors: geibel c. J Chromatogr A. 2021 Apr 26;1643:462069. doi: 10.1016/j.chroma.2021.462069. Epub 2021 Mar 15. J Chromatogr A. 2021. PMID: 33784503

6

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.

Andreev S, Pantsar T, Tesch R, Kahlke N, El-Gokha A, Ansideri F, Grätz L, Romasco J, Sita G, Geibel C, Lämmerhofer M, Tarozzi A, Knapp S, Laufer SA, Koch P. Andreev S, et al. Among authors: geibel c. J Med Chem. 2022 Jan 27;65(2):1283-1301. doi: 10.1021/acs.jmedchem.0c02146. Epub 2021 Jul 2. J Med Chem. 2022. PMID: 34213342

7

Controllable organosilane monolayer density of surface bonding using silatranes for thiol functionalization of silica particles for liquid chromatography and validation of microanalytical method for elemental composition determination.

Geibel C, Theiner J, Wolter M, Kramer M, Lindner W, Lämmerhofer M. Geibel C, et al. J Chromatogr A. 2021 Sep 13;1653:462418. doi: 10.1016/j.chroma.2021.462418. Epub 2021 Jul 22. J Chromatogr A. 2021. PMID: 34340056

8

Enantioselective multiple heart cutting online two-dimensional liquid chromatography-mass spectrometry of all proteinogenic amino acids with second dimension chiral separations in one-minute time scales on a chiral tandem column.

Karongo R, Ge M, Geibel C, Horak J, Lämmerhofer M. Karongo R, et al. Among authors: geibel c. Anal Chim Acta. 2021 Oct 2;1180:338858. doi: 10.1016/j.aca.2021.338858. Epub 2021 Jul 19. Anal Chim Acta. 2021. PMID: 34538327

9

Towards enantioselective ultrahigh performance liquid chromatography-mass spectrometry-based metabolomics of branched-chain fatty acids and anteiso-fatty acids under reversed-phase conditions using sub-2-μm amylose- and cellulose-derived chiral stationary phases.

Geibel C, Zhang L, Serafimov K, Gross H, Lämmerhofer M. Geibel C, et al. Chirality. 2022 Mar;34(3):484-497. doi: 10.1002/chir.23413. Epub 2022 Jan 14. Chirality. 2022. PMID: 35032056

10

High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin.

Aryal N, Chen J, Bhattarai K, Hennrich O, Handayani I, Kramer M, Straetener J, Wommer T, Berscheid A, Peter S, Reiling N, Brötz-Oesterhelt H, Geibel C, Lämmerhofer M, Mast Y, Gross H. Aryal N, et al. Among authors: geibel c. J Nat Prod. 2022 Mar 25;85(3):530-539. doi: 10.1021/acs.jnatprod.1c01051. Epub 2022 Mar 9. J Nat Prod. 2022. PMID: 35263115

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