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Page 1
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Johnson BA, Zhou Y, Lokugamage KG, Vu MN, Bopp N, Crocquet-Valdes PA, Kalveram B, Schindewolf C, Liu Y, Scharton D, Plante JA, Xie X, Aguilar P, Weaver SC, Shi PY, Walker DH, Routh AL, Plante KS, Menachery VD. Johnson BA, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2022 Mar 28:2021.10.14.464390. doi: 10.1101/2021.10.14.464390. bioRxiv. 2022. Update in: PLoS Pathog. 2022 Jun 21;18(6):e1010627. doi: 10.1371/journal.ppat.1010627 PMID: 34671771 Free PMC article. Updated. Preprint.
SARS-CoV-2 Uses Nonstructural Protein 16 to Evade Restriction by IFIT1 and IFIT3.
Schindewolf C, Lokugamage K, Vu MN, Johnson BA, Scharton D, Plante JA, Kalveram B, Crocquet-Valdes PA, Sotcheff S, Jaworski E, Alvarado RE, Debbink K, Daugherty MD, Weaver SC, Routh AL, Walker DH, Plante KS, Menachery VD. Schindewolf C, et al. bioRxiv [Preprint]. 2022 Sep 26:2022.09.26.509529. doi: 10.1101/2022.09.26.509529. bioRxiv. 2022. Update in: J Virol. 2023 Feb 28;97(2):e0153222. doi: 10.1128/jvi.01532-22 PMID: 36203546 Free PMC article. Updated. Preprint.
Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection.
Vu MN, Alvarado RE, Morris DR, Lokugamage KG, Zhou Y, Morgan AL, Estes LK, McLeland AM, Schindewolf C, Plante JA, Ahearn YP, Meyers WM, Murray JT, Crocquet-Valdes PA, Weaver SC, Walker DH, Russell WK, Routh AL, Plante KS, Menachery V. Vu MN, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2023 Jul 10:2023.04.17.536926. doi: 10.1101/2023.04.17.536926. bioRxiv. 2023. PMID: 37131784 Free PMC article. Preprint.
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
Yang Z, Johnson BA, Meliopoulos VA, Ju X, Zhang P, Hughes MP, Wu J, Koreski KP, Chang TC, Wu G, Hixon J, Duffner J, Wong K, Lemieux R, Lokugamage KG, Alvardo RE, Crocquet-Valdes PA, Walker DH, Plante KS, Plante JA, Weaver SC, Kim HJ, Meyers R, Schultz-Cherry S, Ding Q, Menachery VD, Taylor JP. Yang Z, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2023 Jun 30:2023.06.29.546885. doi: 10.1101/2023.06.29.546885. bioRxiv. 2023. Update in: Cell Rep. 2024 Mar 26;43(3):113965. doi: 10.1016/j.celrep.2024.113965 PMID: 37425880 Free PMC article. Updated. Preprint.
SARS-CoV-2 hijacks fragile X mental retardation proteins for efficient infection.
Garvanska DH, Alvarado RE, Mundt FO, Nilsson E, Duel JK, Coscia F, Lindqvist R, Lokugamage K, Johnson BA, Plante JA, Morris DR, Vu MN, Estes LK, McLeland AM, Walker J, Crocquet-Valdes PA, Mendez BL, Plante KS, Walker DH, Weisser MB, Overby AK, Mann M, Menachery VD, Nilsson J. Garvanska DH, et al. bioRxiv [Preprint]. 2023 Sep 1:2023.09.01.555899. doi: 10.1101/2023.09.01.555899. bioRxiv. 2023. PMID: 37693415 Free PMC article. Preprint.
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.
Garvanska DH, Alvarado RE, Mundt FO, Lindqvist R, Duel JK, Coscia F, Nilsson E, Lokugamage K, Johnson BA, Plante JA, Morris DR, Vu MN, Estes LK, McLeland AM, Walker J, Crocquet-Valdes PA, Mendez BL, Plante KS, Walker DH, Weisser MB, Överby AK, Mann M, Menachery VD, Nilsson J. Garvanska DH, et al. EMBO Rep. 2024 Feb;25(2):902-926. doi: 10.1038/s44319-023-00043-z. Epub 2024 Jan 2. EMBO Rep. 2024. PMID: 38177924 Free PMC article.
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Yang Z, Johnson BA, Meliopoulos VA, Ju X, Zhang P, Hughes MP, Wu J, Koreski KP, Clary JE, Chang TC, Wu G, Hixon J, Duffner J, Wong K, Lemieux R, Lokugamage KG, Alvarado RE, Crocquet-Valdes PA, Walker DH, Plante KS, Plante JA, Weaver SC, Kim HJ, Meyers R, Schultz-Cherry S, Ding Q, Menachery VD, Taylor JP. Yang Z, et al. Among authors: lokugamage kg. Cell Rep. 2024 Mar 26;43(3):113965. doi: 10.1016/j.celrep.2024.113965. Epub 2024 Mar 15. Cell Rep. 2024. PMID: 38492217 Free PMC article.
Variant mutation in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation.
Kubinski HC, Despres HW, Johnson BA, Schmidt MM, Jaffrani SA, Mills MG, Lokugamage K, Dumas CM, Shirley DJ, Estes LK, Pekosz A, Crothers JW, Roychoudhury P, Greninger AL, Jerome KR, Di Genova BM, Walker DH, Ballif BA, Ladinsky MS, Bjorkman PJ, Menachery VD, Bruce EA. Kubinski HC, et al. bioRxiv [Preprint]. 2024 Mar 11:2024.03.08.584120. doi: 10.1101/2024.03.08.584120. bioRxiv. 2024. PMID: 38559000 Free PMC article. Preprint.
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
Westendorf K, Žentelis S, Wang L, Foster D, Vaillancourt P, Wiggin M, Lovett E, van der Lee R, Hendle J, Pustilnik A, Sauder JM, Kraft L, Hwang Y, Siegel RW, Chen J, Heinz BA, Higgs RE, Kallewaard NL, Jepson K, Goya R, Smith MA, Collins DW, Pellacani D, Xiang P, de Puyraimond V, Ricicova M, Devorkin L, Pritchard C, O'Neill A, Dalal K, Panwar P, Dhupar H, Garces FA, Cohen CA, Dye JM, Huie KE, Badger CV, Kobasa D, Audet J, Freitas JJ, Hassanali S, Hughes I, Munoz L, Palma HC, Ramamurthy B, Cross RW, Geisbert TW, Menacherry V, Lokugamage K, Borisevich V, Lanz I, Anderson L, Sipahimalani P, Corbett KS, Yang ES, Zhang Y, Shi W, Zhou T, Choe M, Misasi J, Kwong PD, Sullivan NJ, Graham BS, Fernandez TL, Hansen CL, Falconer E, Mascola JR, Jones BE, Barnhart BC. Westendorf K, et al. bioRxiv [Preprint]. 2022 Mar 24:2021.04.30.442182. doi: 10.1101/2021.04.30.442182. bioRxiv. 2022. Update in: Cell Rep. 2022 May 17;39(7):110812. doi: 10.1016/j.celrep.2022.110812 PMID: 33972947 Free PMC article. Updated. Preprint.
SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness.
Zhou Y, Ahearn YP, Lokugamage KG, Alvarado RE, Estes LK, Meyers WM, McLeland AM, Morgan AL, Murray JT, Walker DH, Johnson BA, Routh AL, Menachery VD. Zhou Y, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2024 Nov 13:2024.11.11.622995. doi: 10.1101/2024.11.11.622995. bioRxiv. 2024. PMID: 39605585 Free PMC article. Preprint.
36 results