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Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.
Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX. Wang Z, et al. Among authors: chen j. Am J Physiol Cell Physiol. 2021 Dec 1;321(6):C1010-C1027. doi: 10.1152/ajpcell.00147.2021. Epub 2021 Oct 20. Am J Physiol Cell Physiol. 2021. PMID: 34669509 Free PMC article.
Transplantation of Mesenchymal Stem Cells Attenuates Pulmonary Hypertension by Normalizing the Endothelial-to-Mesenchymal Transition.
Huang J, Lu W, Ouyang H, Chen Y, Zhang C, Luo X, Li M, Shu J, Zheng Q, Chen H, Chen J, Tang H, Sun D, Yuan JX, Yang K, Wang J. Huang J, et al. Among authors: chen j, chen h, chen y. Am J Respir Cell Mol Biol. 2020 Jan;62(1):49-60. doi: 10.1165/rcmb.2018-0165OC. Am J Respir Cell Mol Biol. 2020. PMID: 31211918 Free PMC article.
Structural and functional definition of the pulmonary vein system in a chronic hypoxia-induced pulmonary hypertension rat model.
Wu X, Lu W, He M, Chen H, Chen Y, Duan X, Zheng Q, Li Y, Chen J, Liu S, Liao J, Kuang M, Lin Z, Yang K, Wang J. Wu X, et al. Among authors: chen j, chen h, chen y. Am J Physiol Cell Physiol. 2020 Mar 1;318(3):C555-C569. doi: 10.1152/ajpcell.00289.2019. Epub 2020 Jan 15. Am J Physiol Cell Physiol. 2020. PMID: 31940248 Free article.
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
Chen Y, Lu W, Yang K, Duan X, Li M, Chen X, Zhang J, Kuang M, Liu S, Wu X, Zou G, Liu C, Hong C, He W, Liao J, Hou C, Zhang Z, Zheng Q, Chen J, Zhang N, Tang H, Vanderpool RR, Desai AA, Rischard F, Black SM, Garcia JGN, Makino A, Yuan JX, Zhong N, Wang J. Chen Y, et al. Among authors: chen j, chen x. Br J Pharmacol. 2020 Jun;177(12):2743-2764. doi: 10.1111/bph.15000. Epub 2020 Apr 27. Br J Pharmacol. 2020. PMID: 31976548 Free PMC article.
A novel rat model of pulmonary hypertension induced by mono treatment with SU5416.
Chen Y, Kuang M, Liu S, Hou C, Duan X, Yang K, He W, Liao J, Zheng Q, Zou G, Chen H, Yan H, Chen J, Li Y, Zhou Y, Luo X, Jiang Q, Tang H, Lu W, Wang J. Chen Y, et al. Among authors: chen j, chen h. Hypertens Res. 2020 Aug;43(8):754-764. doi: 10.1038/s41440-020-0457-6. Epub 2020 May 29. Hypertens Res. 2020. PMID: 32472112
Altered Airway Microbiota Composition in Patients With Pulmonary Hypertension.
Zhang C, Zhang T, Lu W, Duan X, Luo X, Liu S, Chen Y, Li Y, Chen J, Liao J, Zhou D, Chen X, Feng H, Gu G, Wang T, Tang H, Makino A, Zhong N, Yuan JX, Yang K, Wang J. Zhang C, et al. Among authors: chen j, chen x, chen y. Hypertension. 2020 Nov;76(5):1589-1599. doi: 10.1161/HYPERTENSIONAHA.120.15025. Epub 2020 Sep 14. Hypertension. 2020. PMID: 32921193
Mitomycin C induces pulmonary vascular endothelial-to-mesenchymal transition and pulmonary veno-occlusive disease via Smad3-dependent pathway in rats.
Zhang C, Lu W, Luo X, Liu S, Li Y, Zheng Q, Liu W, Wu X, Chen Y, Jiang Q, Zhang Z, Gu G, Chen J, Chen H, Liao J, Liu C, Hong C, Tang H, Sun D, Yang K, Wang J. Zhang C, et al. Among authors: chen j, chen h, chen y. Br J Pharmacol. 2021 Jan;178(1):217-235. doi: 10.1111/bph.15314. Epub 2020 Dec 14. Br J Pharmacol. 2021. PMID: 33140842 Free article.
Halofuginone, a promising drug for treatment of pulmonary hypertension.
Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. Jain PP, et al. Among authors: chen j. Br J Pharmacol. 2021 Sep;178(17):3373-3394. doi: 10.1111/bph.15442. Epub 2021 Jul 31. Br J Pharmacol. 2021. PMID: 33694155 Free PMC article.
Upregulation of Piezo1 (Piezo Type Mechanosensitive Ion Channel Component 1) Enhances the Intracellular Free Calcium in Pulmonary Arterial Smooth Muscle Cells From Idiopathic Pulmonary Arterial Hypertension Patients.
Liao J, Lu W, Chen Y, Duan X, Zhang C, Luo X, Lin Z, Chen J, Liu S, Yan H, Chen Y, Feng H, Zhou D, Chen X, Zhang Z, Yang Q, Liu X, Tang H, Li J, Makino A, Yuan JX, Zhong N, Yang K, Wang J. Liao J, et al. Among authors: chen j, chen x, chen y. Hypertension. 2021 Jun;77(6):1974-1989. doi: 10.1161/HYPERTENSIONAHA.120.16629. Epub 2021 Apr 5. Hypertension. 2021. PMID: 33813851
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