Cross AJ - Search Results

1

Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia.

Wolf DH, Zheng D, Kohler C, Turetsky BI, Ruparel K, Satterthwaite TD, Elliott MA, March ME, Cross AJ, Smith MA, Zukin SR, Gur RC, Gur RE. Wolf DH, et al. Among authors: cross aj. Mol Psychiatry. 2022 Feb;27(2):1226-1232. doi: 10.1038/s41380-021-01320-w. Epub 2021 Oct 20. Mol Psychiatry. 2022. PMID: 34667261 Free PMC article. Clinical Trial.

2

AZD8529, a positive allosteric modulator at the mGluR2 receptor, does not improve symptoms in schizophrenia: A proof of principle study.

Litman RE, Smith MA, Doherty JJ, Cross A, Raines S, Gertsik L, Zukin SR. Litman RE, et al. Schizophr Res. 2016 Apr;172(1-3):152-7. doi: 10.1016/j.schres.2016.02.001. Epub 2016 Feb 26. Schizophr Res. 2016. PMID: 26922656 Clinical Trial.

3

AZD6280, a novel partial γ-aminobutyric acid A receptor modulator, demonstrates a pharmacodynamically selective effect profile in healthy male volunteers.

Chen X, Jacobs G, de Kam ML, Jaeger J, Lappalainen J, Maruff P, Smith MA, Cross AJ, Cohen A, van Gerven J. Chen X, et al. Among authors: cross aj. J Clin Psychopharmacol. 2015 Feb;35(1):22-33. doi: 10.1097/JCP.0000000000000251. J Clin Psychopharmacol. 2015. PMID: 25493397 Clinical Trial.

4

A randomized, placebo-controlled pilot trial of the delta opioid receptor agonist AZD2327 in anxious depression.

Richards EM, Mathews DC, Luckenbaugh DA, Ionescu DF, Machado-Vieira R, Niciu MJ, Duncan WC, Nolan NM, Franco-Chaves JA, Hudzik T, Maciag C, Li S, Cross A, Smith MA, Zarate CA Jr. Richards EM, et al. Psychopharmacology (Berl). 2016 Mar;233(6):1119-30. doi: 10.1007/s00213-015-4195-4. Epub 2016 Jan 4. Psychopharmacology (Berl). 2016. PMID: 26728893 Free PMC article. Clinical Trial.

5

The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys.

Justinova Z, Panlilio LV, Secci ME, Redhi GH, Schindler CW, Cross AJ, Mrzljak L, Medd A, Shaham Y, Goldberg SR. Justinova Z, et al. Among authors: cross aj. Biol Psychiatry. 2015 Oct 1;78(7):452-62. doi: 10.1016/j.biopsych.2015.01.014. Epub 2015 Feb 7. Biol Psychiatry. 2015. PMID: 25802079 Free PMC article.

6

From bench to bedside: mGluR2 positive allosteric modulators as medications to treat substance use disorders.

Acri JB, Cross AJ, Skolnick P. Acri JB, et al. Among authors: cross aj. Psychopharmacology (Berl). 2017 May;234(9-10):1347-1355. doi: 10.1007/s00213-016-4501-9. Epub 2016 Dec 20. Psychopharmacology (Berl). 2017. PMID: 27995279 Review.

7

The central nervous system effects of the partial GABA-Aα2,3 -selective receptor modulator AZD7325 in comparison with lorazepam in healthy males.

Chen X, Jacobs G, de Kam M, Jaeger J, Lappalainen J, Maruff P, Smith MA, Cross AJ, Cohen A, van Gerven J. Chen X, et al. Among authors: cross aj. Br J Clin Pharmacol. 2014 Dec;78(6):1298-314. doi: 10.1111/bcp.12413. Br J Clin Pharmacol. 2014. PMID: 24802722 Free PMC article. Clinical Trial.

8

Attenuation of nicotine-taking and nicotine-seeking behavior by the mGlu2 receptor positive allosteric modulators AZD8418 and AZD8529 in rats.

Li X, D'Souza MS, Niño AM, Doherty J, Cross A, Markou A. Li X, et al. Psychopharmacology (Berl). 2016 May;233(10):1801-14. doi: 10.1007/s00213-016-4220-2. Epub 2016 Feb 13. Psychopharmacology (Berl). 2016. PMID: 26873083

9

Metabotropic Glutamate Receptors 2 and 3 as Targets for Treating Nicotine Addiction.

Cross AJ, Anthenelli R, Li X. Cross AJ, et al. Biol Psychiatry. 2018 Jun 1;83(11):947-954. doi: 10.1016/j.biopsych.2017.11.021. Epub 2017 Nov 21. Biol Psychiatry. 2018. PMID: 29301614 Free PMC article. Review.

10

The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats.

Augier E, Dulman RS, Rauffenbart C, Augier G, Cross AJ, Heilig M. Augier E, et al. Among authors: cross aj. Neuropsychopharmacology. 2016 Nov;41(12):2932-2940. doi: 10.1038/npp.2016.107. Epub 2016 Jun 24. Neuropsychopharmacology. 2016. PMID: 27339394 Free PMC article.

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