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Proteolysis-targeting influenza vaccine strains induce broad-spectrum immunity and in vivo protection.
Shen J, Li J, Shen Q, Hou J, Zhang C, Bai H, Ai X, Su Y, Wang Z, Zhang Y, Xu B, Hao J, Wang P, Zhang Q, Ye AY, Li Z, Feng T, Li L, Qi F, Wang Q, Sun Y, Liu C, Xi X, Yan L, Hong H, Chen Y, Xie X, Xie J, Liu X, Du R, Plebani R, Zhang L, Zhou D, Church G, Si L. Shen J, et al. Among authors: si l. Nat Microbiol. 2025 Jan 15. doi: 10.1038/s41564-024-01908-2. Online ahead of print. Nat Microbiol. 2025. PMID: 39815008
PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins.
Zhang C, Hou J, Li Z, Shen Q, Bai H, Chen L, Shen J, Wang P, Su Y, Li J, Zhang Q, Liu C, Xi X, Qi F, Chen Y, Xie X, Ye AY, Liu X, Plebani R, Church G, Si L. Zhang C, et al. Among authors: si l. Nat Chem Biol. 2025 Jan 15. doi: 10.1038/s41589-024-01813-z. Online ahead of print. Nat Chem Biol. 2025. PMID: 39814992
1,223 results