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Microscale purification in support of high-throughput medicinal chemistry.
Barhate CL, Donnell AF, Davies M, Li L, Zhang Y, Yang F, Black R, Zipp G, Zhang Y, Cavallaro CL, Priestley ES, Weller HN. Barhate CL, et al. Among authors: cavallaro cl. Chem Commun (Camb). 2021 Oct 21;57(84):11037-11040. doi: 10.1039/d1cc03791a. Chem Commun (Camb). 2021. PMID: 34608906
Discovery and SAR of aryl hydroxy pyrimidinones as potent small molecule agonists of the GPCR APJ.
Myers MC, Bilder DM, Cavallaro CL, Chao HJ, Su S, Burford NT, Nayeem A, Wang T, Yan M, Langish RA, Dabros M, Li YX, Rose AV, Behnia K, Onorato JM, Gargalovic PS, Wexler RR, Lawrence RM. Myers MC, et al. Among authors: cavallaro cl. Bioorg Med Chem Lett. 2020 Apr 1;30(7):126955. doi: 10.1016/j.bmcl.2020.126955. Epub 2020 Jan 22. Bioorg Med Chem Lett. 2020. PMID: 32035698
Ligand and Target Discovery by Fragment-Based Screening in Human Cells.
Parker CG, Galmozzi A, Wang Y, Correia BE, Sasaki K, Joslyn CM, Kim AS, Cavallaro CL, Lawrence RM, Johnson SR, Narvaiza I, Saez E, Cravatt BF. Parker CG, et al. Among authors: cavallaro cl. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19. Cell. 2017. PMID: 28111073 Free PMC article.
Synthesis of Differentially Protected Azatryptophan Analogs via Pd2(dba)3/XPhos Catalyzed Negishi Coupling of N-Ts Azaindole Halides with Zinc Derivative from Fmoc-Protected tert-Butyl (R)-2-Amino-3-iodopropanoate.
Nimje RY, Vytla D, Kuppusamy P, Velayuthaperumal R, Jarugu LB, Reddy CA, Chikkananjaiah NK, Rampulla RA, Cavallaro CL, Li J, Mathur A, Gupta A, Roy A. Nimje RY, et al. Among authors: cavallaro cl. J Org Chem. 2020 Sep 4;85(17):11519-11530. doi: 10.1021/acs.joc.0c00973. Epub 2020 Aug 25. J Org Chem. 2020. PMID: 32786620
A statistical-based approach to assessing the fidelity of combinatorial libraries encoded with electrophoric molecular tags. Development and application of tag decode-assisted single bead LC/MS analysis.
Dolle RE, Guo J, O'Brien L, Jin Y, Piznik M, Bowman KJ, Li W, Egan WJ, Cavallaro CL, Roughton AL, Zhao Q, Reader JC, Orlowski M, Jacob-Samuel B, Carroll CD. Dolle RE, et al. Among authors: cavallaro cl. J Comb Chem. 2000 Nov-Dec;2(6):716-31. doi: 10.1021/cc000052k. J Comb Chem. 2000. PMID: 11126300
21 results