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Page 1
Enhancer-associated H3K4 methylation safeguards in vitro germline competence.
Bleckwehl T, Crispatzu G, Schaaf K, Respuela P, Bartusel M, Benson L, Clark SJ, Dorighi KM, Barral A, Laugsch M, van IJcken WFJ, Manzanares M, Wysocka J, Reik W, Rada-Iglesias Á. Bleckwehl T, et al. Nat Commun. 2021 Oct 1;12(1):5771. doi: 10.1038/s41467-021-26065-6. Nat Commun. 2021. PMID: 34599190 Free PMC article.
Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness.
Pachano T, Sánchez-Gaya V, Ealo T, Mariner-Faulí M, Bleckwehl T, Asenjo HG, Respuela P, Cruz-Molina S, Muñoz-San Martín M, Haro E, van IJcken WFJ, Landeira D, Rada-Iglesias A. Pachano T, et al. Among authors: bleckwehl t. Nat Genet. 2021 Jul;53(7):1036-1049. doi: 10.1038/s41588-021-00888-x. Epub 2021 Jun 28. Nat Genet. 2021. PMID: 34183853 Free PMC article.
Modeling the Pathological Long-Range Regulatory Effects of Human Structural Variation with Patient-Specific hiPSCs.
Laugsch M, Bartusel M, Rehimi R, Alirzayeva H, Karaolidou A, Crispatzu G, Zentis P, Nikolic M, Bleckwehl T, Kolovos P, van Ijcken WFJ, Šarić T, Koehler K, Frommolt P, Lachlan K, Baptista J, Rada-Iglesias A. Laugsch M, et al. Among authors: bleckwehl t. Cell Stem Cell. 2019 May 2;24(5):736-752.e12. doi: 10.1016/j.stem.2019.03.004. Epub 2019 Apr 11. Cell Stem Cell. 2019. PMID: 30982769 Free article.
Encompassing view of spatial and single-cell RNA sequencing renews the role of the microvasculature in human atherosclerosis.
Bleckwehl T, Babler A, Tebens M, Maryam S, Nyberg M, Bosteen M, Halder M, Shaw I, Fleig S, Pyke C, Hvid H, Voetmann LM, van Buul JD, Sluimer JC, Das V, Baumgart S, Kramann R, Hayat S. Bleckwehl T, et al. Nat Cardiovasc Res. 2024 Dec 23. doi: 10.1038/s44161-024-00582-1. Online ahead of print. Nat Cardiovasc Res. 2024. PMID: 39715784
Label-free single-cell RNA multiplexing leveraging genetic variability.
Hoeft K, Bleckwehl T, Schumacher D, Kim H, Meyer R, Long Q, Zhang L, Möller C, Clahsen-van Groningen MC, Babler A, Saritas T, Kurth I, Milting H, Hayat S, Kramann R. Hoeft K, et al. Among authors: bleckwehl t. Nat Commun. 2024 Dec 5;15(1):10612. doi: 10.1038/s41467-024-54270-6. Nat Commun. 2024. PMID: 39638798 Free PMC article.
Targeting immune-fibroblast cell communication in heart failure.
Amrute JM, Luo X, Penna V, Yang S, Yamawaki T, Hayat S, Bredemeyer A, Jung IH, Kadyrov FF, Heo GS, Venkatesan R, Shi SY, Parvathaneni A, Koenig AL, Kuppe C, Baker C, Luehmann H, Jones C, Kopecky B, Zeng X, Bleckwehl T, Ma P, Lee P, Terada Y, Fu A, Furtado M, Kreisel D, Kovacs A, Stitziel NO, Jackson S, Li CM, Liu Y, Rosenthal NA, Kramann R, Ason B, Lavine KJ. Amrute JM, et al. Among authors: bleckwehl t. Nature. 2024 Nov;635(8038):423-433. doi: 10.1038/s41586-024-08008-5. Epub 2024 Oct 23. Nature. 2024. PMID: 39443792
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner.
Hoeft K, Schaefer GJL, Kim H, Schumacher D, Bleckwehl T, Long Q, Klinkhammer BM, Peisker F, Koch L, Nagai J, Halder M, Ziegler S, Liehn E, Kuppe C, Kranz J, Menzel S, Costa I, Wahida A, Boor P, Schneider RK, Hayat S, Kramann R. Hoeft K, et al. Among authors: bleckwehl t. Cell Rep. 2023 Feb 28;42(2):112131. doi: 10.1016/j.celrep.2023.112131. Epub 2023 Feb 18. Cell Rep. 2023. PMID: 36807143 Free PMC article.
13 results