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Targeted Protein Acetylation in Cells Using Heterobifunctional Molecules.
Wang WW, Chen LY, Wozniak JM, Jadhav AM, Anderson H, Malone TE, Parker CG. Wang WW, et al. Among authors: parker cg. J Am Chem Soc. 2021 Oct 13;143(40):16700-16708. doi: 10.1021/jacs.1c07850. Epub 2021 Sep 30. J Am Chem Soc. 2021. PMID: 34592107 Free PMC article.
The Druggability of Solute Carriers.
Wang WW, Gallo L, Jadhav A, Hawkins R, Parker CG. Wang WW, et al. Among authors: parker cg. J Med Chem. 2020 Apr 23;63(8):3834-3867. doi: 10.1021/acs.jmedchem.9b01237. Epub 2019 Dec 19. J Med Chem. 2020. PMID: 31774679 Review.
A Chemical Proteomic Map of Heme-Protein Interactions.
Homan RA, Jadhav AM, Conway LP, Parker CG. Homan RA, et al. Among authors: parker cg. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12. J Am Chem Soc. 2022. PMID: 35960875 Free PMC article.
Enhanced mapping of small-molecule binding sites in cells.
Wozniak JM, Li W, Governa P, Chen LY, Jadhav A, Dongre A, Forli S, Parker CG. Wozniak JM, et al. Among authors: parker cg. Nat Chem Biol. 2024 Jul;20(7):823-834. doi: 10.1038/s41589-023-01514-z. Epub 2024 Jan 2. Nat Chem Biol. 2024. PMID: 38167919 Free PMC article.
Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity.
Chiu TY, Lazar DC, Wang WW, Wozniak JM, Jadhav AM, Li W, Gazaniga N, Theofilopoulos AN, Teijaro JR, Parker CG. Chiu TY, et al. Among authors: parker cg. Nat Chem Biol. 2024 Aug;20(8):1000-1011. doi: 10.1038/s41589-023-01527-8. Epub 2024 Jan 8. Nat Chem Biol. 2024. PMID: 38191941 Free PMC article.
Mechanistic differences between linear vs. spirocyclic dialkyldiazirine probes for photoaffinity labeling.
O'Brien JGK, Conway LP, Ramaraj PK, Jadhav AM, Jin J, Dutra JK, Evers P, Masoud SS, Schupp M, Saridakis I, Chen Y, Maulide N, Pezacki JP, Am Ende CW, Parker CG, Fox JM. O'Brien JGK, et al. Among authors: parker cg. Chem Sci. 2024 Aug 13;15(37):15463-73. doi: 10.1039/d4sc04238g. Online ahead of print. Chem Sci. 2024. PMID: 39246352 Free PMC article.
77 results