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The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops.
Ottema S, Mulet-Lazaro R, Erpelinck-Verschueren C, van Herk S, Havermans M, Arricibita Varea A, Vermeulen M, Beverloo HB, Gröschel S, Haferlach T, Haferlach C, J Wouters B, Bindels E, Smeenk L, Delwel R. Ottema S, et al. Among authors: erpelinck verschueren c. Nat Commun. 2021 Sep 28;12(1):5679. doi: 10.1038/s41467-021-25862-3. Nat Commun. 2021. PMID: 34584081 Free PMC article.
Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.
Wouters BJ, Jordà MA, Keeshan K, Louwers I, Erpelinck-Verschueren CA, Tielemans D, Langerak AW, He Y, Yashiro-Ohtani Y, Zhang P, Hetherington CJ, Verhaak RG, Valk PJ, Löwenberg B, Tenen DG, Pear WS, Delwel R. Wouters BJ, et al. Blood. 2007 Nov 15;110(10):3706-14. doi: 10.1182/blood-2007-02-073486. Epub 2007 Aug 1. Blood. 2007. PMID: 17671232 Free PMC article.
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.
Figueroa ME, Lugthart S, Li Y, Erpelinck-Verschueren C, Deng X, Christos PJ, Schifano E, Booth J, van Putten W, Skrabanek L, Campagne F, Mazumdar M, Greally JM, Valk PJ, Löwenberg B, Delwel R, Melnick A. Figueroa ME, et al. Cancer Cell. 2010 Jan 19;17(1):13-27. doi: 10.1016/j.ccr.2009.11.020. Epub 2010 Jan 7. Cancer Cell. 2010. PMID: 20060365 Free PMC article.
Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.
Lugthart S, Figueroa ME, Bindels E, Skrabanek L, Valk PJ, Li Y, Meyer S, Erpelinck-Verschueren C, Greally J, Löwenberg B, Melnick A, Delwel R. Lugthart S, et al. Among authors: erpelinck verschueren c. Blood. 2011 Jan 6;117(1):234-41. doi: 10.1182/blood-2010-04-281337. Epub 2010 Sep 20. Blood. 2011. PMID: 20855866 Free PMC article.
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia.
Ribeiro AF, Pratcorona M, Erpelinck-Verschueren C, Rockova V, Sanders M, Abbas S, Figueroa ME, Zeilemaker A, Melnick A, Löwenberg B, Valk PJ, Delwel R. Ribeiro AF, et al. Among authors: erpelinck verschueren c. Blood. 2012 Jun 14;119(24):5824-31. doi: 10.1182/blood-2011-07-367961. Epub 2012 Apr 5. Blood. 2012. PMID: 22490330 Free article.
Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia.
Olofsen PA, Fatrai S, van Strien PMH, Obenauer JC, de Looper HWJ, Hoogenboezem RM, Erpelinck-Verschueren CAJ, Vermeulen MPWM, Roovers O, Haferlach T, Jansen JH, Ghazvini M, Bindels EMJ, Schneider RK, de Pater EM, Touw IP. Olofsen PA, et al. Among authors: erpelinck verschueren caj. Cell Rep Med. 2020 Aug 25;1(5):100074. doi: 10.1016/j.xcrm.2020.100074. eCollection 2020 Aug 25. Cell Rep Med. 2020. PMID: 33205068 Free PMC article.
Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia.
Smeenk L, Ottema S, Mulet-Lazaro R, Ebert A, Havermans M, Varea AA, Fellner M, Pastoors D, van Herk S, Erpelinck-Verschueren C, Grob T, Hoogenboezem RM, Kavelaars FG, Matson DR, Bresnick EH, Bindels EM, Kentsis A, Zuber J, Delwel R. Smeenk L, et al. Among authors: erpelinck verschueren c. Cancer Discov. 2021 Nov;11(11):2868-2883. doi: 10.1158/2159-8290.CD-20-1793. Epub 2021 May 12. Cancer Discov. 2021. PMID: 33980539 Free PMC article.
22 results