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Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity.
Brehmer D, Beke L, Wu T, Millar HJ, Moy C, Sun W, Mannens G, Pande V, Boeckx A, van Heerde E, Nys T, Gustin EM, Verbist B, Zhou L, Fan Y, Bhargava V, Safabakhsh P, Vinken P, Verhulst T, Gilbert A, Rai S, Graubert TA, Pastore F, Fiore D, Gu J, Johnson A, Philippar U, Morschhäuser B, Walker D, De Lange D, Keersmaekers V, Viellevoye M, Diels G, Schepens W, Thuring JW, Meerpoel L, Packman K, Lorenzi MV, Laquerre S. Brehmer D, et al. Among authors: zhou l. Mol Cancer Ther. 2021 Dec;20(12):2317-2328. doi: 10.1158/1535-7163.MCT-21-0367. Epub 2021 Sep 28. Mol Cancer Ther. 2021. PMID: 34583982 Free PMC article.
Efficacy, safety, and pharmacokinetics of teclistamab in Chinese patients with relapsed/refractory multiple myeloma from the China cohort of MajesTEC-1.
Cai Z, Xia Z, He AL, Dong YJ, Wang Y, Liao A, Song Y, Song Mm J, Uhlar C, Chastain K, Watkins L, Luo X, Huang L, Niu Z, Quijano Cardé NA, Guo Y, Xu H, Verona RI, Zhou L, Li J, Fu W, Niu T, Du J. Cai Z, et al. Among authors: zhou l. Cancer. 2025 Jan 1;131(1):e35665. doi: 10.1002/cncr.35665. Epub 2024 Dec 11. Cancer. 2025. PMID: 39660861 Free PMC article. Clinical Trial.
Immune profiling of patients with extranodal natural killer/T cell lymphoma treated with daratumumab.
Qing M, Zhou T, Perova T, Abraham Y, Sweeney C, Krevvata M, Zhang X, Qi M, Gao G, Kim TM, Yao M, Cho SG, Eom HS, Lim ST, Yeh SP, Kwong YL, Yoon DH, Kim JS, Kim WS, Zhou L, Attar R, Verona RI. Qing M, et al. Among authors: zhou t, zhou l. Ann Hematol. 2024 Jun;103(6):1989-2001. doi: 10.1007/s00277-023-05603-w. Epub 2024 Jan 18. Ann Hematol. 2024. PMID: 38233570 Free PMC article. Clinical Trial.
DCFE-YOLO: A novel fabric defect detection method.
Zhou L, Ma B, Dong Y, Yin Z, Lu F. Zhou L, et al. PLoS One. 2025 Jan 14;20(1):e0314525. doi: 10.1371/journal.pone.0314525. eCollection 2025. PLoS One. 2025. PMID: 39808621
TRAIL agonists rescue mice from radiation-induced lung, skin or esophageal injury.
Strandberg J, Louie A, Lee S, Hahn M, Srinivasan P, George A, De La Cruz A, Zhang L, Hernandez Borrero L, Huntington KE, De La Cruz P, Seyhan AA, Koffer PP, Wazer DE, DiPetrillo TA, Graff SL, Azzoli CG, Rounds SI, Klein-Szanto AJ, Tavora F, Yakirevich E, Abbas AE, Zhou L, El-Deiry WS. Strandberg J, et al. Among authors: zhou l. J Clin Invest. 2025 Jan 14:e173649. doi: 10.1172/JCI173649. Online ahead of print. J Clin Invest. 2025. PMID: 39808500
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