Vinken P - Search Results

1

Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity.

Brehmer D, Beke L, Wu T, Millar HJ, Moy C, Sun W, Mannens G, Pande V, Boeckx A, van Heerde E, Nys T, Gustin EM, Verbist B, Zhou L, Fan Y, Bhargava V, Safabakhsh P, Vinken P, Verhulst T, Gilbert A, Rai S, Graubert TA, Pastore F, Fiore D, Gu J, Johnson A, Philippar U, Morschhäuser B, Walker D, De Lange D, Keersmaekers V, Viellevoye M, Diels G, Schepens W, Thuring JW, Meerpoel L, Packman K, Lorenzi MV, Laquerre S. Brehmer D, et al. Among authors: vinken p. Mol Cancer Ther. 2021 Dec;20(12):2317-2328. doi: 10.1158/1535-7163.MCT-21-0367. Epub 2021 Sep 28. Mol Cancer Ther. 2021. PMID: 34583982 Free PMC article.

2

Renal tubular and adrenal medullary tumors in the 2-year rat study with canagliflozin confirmed to be secondary to carbohydrate (glucose) malabsorption in the 15-month mechanistic rat study.

De Jonghe S, Johnson MD, Mamidi RNVS, Vinken P, Feyen B, Lammens G, Proctor J. De Jonghe S, et al. Among authors: vinken p. Chem Biol Interact. 2017 Nov 1;277:85-90. doi: 10.1016/j.cbi.2017.09.008. Epub 2017 Sep 12. Chem Biol Interact. 2017. PMID: 28916336

3

A canine model to evaluate efficacy and safety of γ-secretase inhibitors and modulators.

Borghys H, Tuefferd M, Van Broeck B, Clessens E, Dillen L, Cools W, Vinken P, Straetemans R, De Ridder F, Gijsen H, Mercken M. Borghys H, et al. Among authors: vinken p. J Alzheimers Dis. 2012;28(4):809-22. doi: 10.3233/JAD-2011-111475. J Alzheimers Dis. 2012. PMID: 22072214

4

Carbohydrate malabsorption mechanism for tumor formation in rats treated with the SGLT2 inhibitor canagliflozin.

Mamidi RN, Proctor J, De Jonghe S, Feyen B, Moesen E, Vinken P, Ma JY, Bryant S, Snook S, Louden C, Lammens G, Ways K, Kelley MF, Johnson MD. Mamidi RN, et al. Among authors: vinken p. Chem Biol Interact. 2014 Sep 25;221:109-18. doi: 10.1016/j.cbi.2014.08.001. Epub 2014 Aug 14. Chem Biol Interact. 2014. PMID: 25130857

5

Carcinogenicity in rats of the SGLT2 inhibitor canagliflozin.

De Jonghe S, Proctor J, Vinken P, Feyen B, Wynant I, Marien D, Geys H, Mamidi RN, Johnson MD. De Jonghe S, et al. Among authors: vinken p. Chem Biol Interact. 2014 Dec 5;224:1-12. doi: 10.1016/j.cbi.2014.09.018. Epub 2014 Oct 5. Chem Biol Interact. 2014. PMID: 25289773

6

Bilateral Symmetrical Idiopathic Necrotizing Encephalopathy: A New Syndrome in Sprague-Dawley Rats.

De Jonghe S, Abbott D, Vinken P, Moesen E, Feyen B, Lammens L, Vynckier A, De Lahunta A. De Jonghe S, et al. Among authors: vinken p. Toxicol Pathol. 2015 Dec;43(8):1141-8. doi: 10.1177/0192623315604409. Epub 2015 Oct 27. Toxicol Pathol. 2015. PMID: 26511844

7

Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat.

Thomson PJ, Kafu L, Meng X, Snoeys J, De Bondt A, De Maeyer D, Wils H, Leclercq L, Vinken P, Naisbitt DJ. Thomson PJ, et al. Among authors: vinken p. Allergy. 2021 Jun;76(6):1825-1835. doi: 10.1111/all.14652. Epub 2020 Nov 24. Allergy. 2021. PMID: 33150583

8

MODELING ANTI-KLH ELISA DATA USING TWO-STAGE AND MIXED EFFECTS MODELS IN SUPPORT OF IMMUNOTOXICOLOGICAL STUDIES.

Shkedy Z, Straetemans R, Molenberghs G, Desmidt M, Vinken P, Goeminne N, Coussement W, Poel BVD, Bijnens L. Shkedy Z, et al. Among authors: vinken p. J Biopharm Stat. 2005;15(2):205-223. doi: 10.1081/BIP-200048815. J Biopharm Stat. 2005. PMID: 28881177

9

Evaluation of the diagnostic potential of urinary N-Acetyltyramine-O,β-glucuronide (NATOG) as diagnostic biomarker for Onchocerca volvulus infection.

Lagatie O, Njumbe Ediage E, Batsa Debrah L, Diels L, Nolten C, Vinken P, Debrah A, Dillen L, Silber S, Stuyver LJ. Lagatie O, et al. Among authors: vinken p. Parasit Vectors. 2016 May 23;9(1):302. doi: 10.1186/s13071-016-1582-6. Parasit Vectors. 2016. PMID: 27216752 Free PMC article.

10

Chronic drug-induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell-derived cardiomyocytes.

Kopljar I, De Bondt A, Vinken P, Teisman A, Damiano B, Goeminne N, Van den Wyngaert I, Gallacher DJ, Lu HR. Kopljar I, et al. Among authors: vinken p. Br J Pharmacol. 2017 Nov;174(21):3766-3779. doi: 10.1111/bph.13713. Epub 2017 Feb 8. Br J Pharmacol. 2017. PMID: 28094846 Free PMC article.

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