Hroch M - Search Results

1

Differential adsorption of an analyte and its D₄, D₅ and ¹³C₆ labeled analogues combined with instrument-specific carry-over issues: The Achilles' heel of ibrutinib TDM.

Mžik M, Váňová N, Kriegelstein M, Hroch M. Mžik M, et al. Among authors: hroch m. J Pharm Biomed Anal. 2021 Nov 30;206:114366. doi: 10.1016/j.jpba.2021.114366. Epub 2021 Sep 14. J Pharm Biomed Anal. 2021. PMID: 34555634

2

LC-MS/MS method for the determination of haemanthamine in rat plasma, bile and urine and its application to a pilot pharmacokinetic study.

Hroch M, Mičuda S, Havelek R, Cermanová J, Cahlíková L, Hošťálková A, Hulcová D, Řezáčová M. Hroch M, et al. Biomed Chromatogr. 2016 Jul;30(7):1083-1091. doi: 10.1002/bmc.3653. Epub 2015 Dec 13. Biomed Chromatogr. 2016. PMID: 26577707

3

The New Acetylcholinesterase Inhibitors PC-37 and PC-48 (7-Methoxytacrine-Donepezil-Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats.

Zdarova Karasova J, Mzik M, Hroch M, Korabecny J, Nepovimova E, Vorisek V, Palicka V, Kuca K. Zdarova Karasova J, et al. Among authors: hroch m. Basic Clin Pharmacol Toxicol. 2018 Apr;122(4):373-382. doi: 10.1111/bcpt.12922. Epub 2017 Dec 15. Basic Clin Pharmacol Toxicol. 2018. PMID: 29067789 Free article.

4

In vitro and in vivo metabolism of 3-quinuclidinyl benzilate by high-resolution mass spectrometry.

Uher M, Mžik M, Karasová JŽ, Herman D, Čechová L, Dlabková A, Mrkvicová A, Hroch M. Uher M, et al. Among authors: hroch m. J Pharm Biomed Anal. 2020 Oct 25;190:113519. doi: 10.1016/j.jpba.2020.113519. Epub 2020 Aug 1. J Pharm Biomed Anal. 2020. PMID: 32795780

5

3-Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats.

Dlabkova A, Herman D, Cechova L, Hroch M, Vanova N, Zdarova Karasova J. Dlabkova A, et al. Among authors: hroch m. Basic Clin Pharmacol Toxicol. 2021 Sep;129(3):246-255. doi: 10.1111/bcpt.13627. Epub 2021 Jun 30. Basic Clin Pharmacol Toxicol. 2021. PMID: 34145973 Free article.

6

Synthesis of [¹³ C₆ ]-ibrutinib.

Kriegelstein M, Hroch M, Marek A. Kriegelstein M, et al. Among authors: hroch m. J Labelled Comp Radiopharm. 2021 Nov;64(13):500-512. doi: 10.1002/jlcr.3944. Epub 2021 Sep 20. J Labelled Comp Radiopharm. 2021. PMID: 34478181

7

UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data.

Mzik M, Sestak V, Mezeiova E, Korabecny J, Hroch M, Pejchal J, Karasova-Zdarova J. Mzik M, et al. Among authors: hroch m. J Pharm Biomed Anal. 2022 Sep 20;219:114898. doi: 10.1016/j.jpba.2022.114898. Epub 2022 Jun 21. J Pharm Biomed Anal. 2022. PMID: 35779353

8

High-throughput salting-out assisted liquid-liquid extraction using a 3D printed device and its application in the quantification of ibrutinib and its metabolite PCI-45227 in human serum.

Écsiová D, Šimkovič M, Uher M, Hroch M. Écsiová D, et al. Among authors: hroch m. J Pharm Biomed Anal. 2022 Sep 20;219:114923. doi: 10.1016/j.jpba.2022.114923. Epub 2022 Jul 2. J Pharm Biomed Anal. 2022. PMID: 35830774

9

Direct Multi-Deuterium Labelling of Pirtobrutinib.

Kriegelstein M, Hojcsková J, Hroch M, Marek A. Kriegelstein M, et al. Among authors: hroch m. J Labelled Comp Radiopharm. 2024 Jul;67(9):314-323. doi: 10.1002/jlcr.4117. Epub 2024 Jul 14. J Labelled Comp Radiopharm. 2024. PMID: 39004786

10

HPLC determination of arginases inhibitor N-(ω)-hydroxy-nor-L-arginine using core-shell particle column and LC-MS/MS identification of principal metabolite in rat plasma.

Hroch M, Havlínová Z, Nobilis M, Chládek J. Hroch M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jan 1;880(1):90-9. doi: 10.1016/j.jchromb.2011.11.022. Epub 2011 Nov 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22142597

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