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Murine nuclear tyrosyl-tRNA synthetase deficiency leads to fat storage deficiency and hearing loss.
Jones JA, Zhou J, Dong J, Huitron-Resendiz S, Boussaty E, Chavez E, Wei N, Dumitru CD, Morodomi Y, Kanaji T, Ryan AF, Friedman R, Zhou T, Kanaji S, Wortham M, Schenk S, Roberts AJ, Yang XL. Jones JA, et al. Among authors: dumitru cd. J Biol Chem. 2024 Oct;300(10):107756. doi: 10.1016/j.jbc.2024.107756. Epub 2024 Sep 12. J Biol Chem. 2024. PMID: 39260699 Free PMC article.
CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.
He W, Bai G, Zhou H, Wei N, White NM, Lauer J, Liu H, Shi Y, Dumitru CD, Lettieri K, Shubayev V, Jordanova A, Guergueltcheva V, Griffin PR, Burgess RW, Pfaff SL, Yang XL. He W, et al. Among authors: dumitru cd. Nature. 2015 Oct 29;526(7575):710-4. doi: 10.1038/nature15510. Epub 2015 Oct 21. Nature. 2015. PMID: 26503042 Free PMC article.
25 results