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Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques.
Rosati M, Agarwal M, Hu X, Devasundaram S, Stellas D, Chowdhury B, Bear J, Burns R, Donohue D, Pessaint L, Andersen H, Lewis MG, Terpos E, Dimopoulos MA, Wlodawer A, Mullins JI, Venzon DJ, Pavlakis GN, Felber BK. Rosati M, et al. Among authors: wlodawer a. PLoS Pathog. 2021 Sep 22;17(9):e1009701. doi: 10.1371/journal.ppat.1009701. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34551020 Free PMC article.
A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication.
Hattori SI, Higashi-Kuwata N, Hayashi H, Allu SR, Raghavaiah J, Bulut H, Das D, Anson BJ, Lendy EK, Takamatsu Y, Takamune N, Kishimoto N, Murayama K, Hasegawa K, Li M, Davis DA, Kodama EN, Yarchoan R, Wlodawer A, Misumi S, Mesecar AD, Ghosh AK, Mitsuya H. Hattori SI, et al. Among authors: wlodawer a. Nat Commun. 2021 Jan 28;12(1):668. doi: 10.1038/s41467-021-20900-6. Nat Commun. 2021. PMID: 33510133 Free PMC article.
Editor Profile: Alexander Wlodawer.
FEBS Journal Editorial Team; Wlodawer A. FEBS Journal Editorial Team, et al. Among authors: wlodawer a. FEBS J. 2021 Dec;288(24):6848-6849. doi: 10.1111/febs.15887. FEBS J. 2021. PMID: 34927814 Free article.
Structural and virologic mechanism of the emergence of resistance to Mpro inhibitors in SARS-CoV-2.
Hattori SI, Bulut H, Hayashi H, Kishimoto N, Takamune N, Hasegawa K, Furusawa Y, Yamayoshi S, Murayama K, Tamamura H, Li M, Wlodawer A, Kawaoka Y, Misumi S, Mitsuya H. Hattori SI, et al. Among authors: wlodawer a. Proc Natl Acad Sci U S A. 2024 Sep 10;121(37):e2404175121. doi: 10.1073/pnas.2404175121. Epub 2024 Sep 5. Proc Natl Acad Sci U S A. 2024. PMID: 39236245 Free PMC article.
Protein crystallography: alive and well.
Wlodawer A. Wlodawer A. FEBS J. 2021 Oct;288(20):5786-5787. doi: 10.1111/febs.15822. Epub 2021 Mar 24. FEBS J. 2021. PMID: 33759375 Free article.
386 results