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The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload.
Videira RF, Koop AMC, Ottaviani L, Poels EM, Kocken JMM, Dos Remedios C, Mendes-Ferreira P, Van De Kolk KW, Du Marchie Sarvaas GJ, Lourenço A, Llucià-Valldeperas A, Nascimento DA, De Windt LJ, De Man FS, Falcão-Pires I, Berger RMF, da Costa Martins PA. Videira RF, et al. Among authors: koop amc. Cardiovasc Res. 2022 Sep 20;118(12):2688-2702. doi: 10.1093/cvr/cvab299. Cardiovasc Res. 2022. PMID: 34550326 Free PMC article.
Neuregulin-1 enhances cell-cycle activity, delays cardiac fibrosis, and improves cardiac performance in rat pups with right ventricular pressure load.
Bossers GPL, Günthel M, van der Feen DE, Hagdorn QAJ, Koop AC, van Duijvenboden K, Barnett P, Borgdorff MAJ, Christoffels VM, Silljé HHW, Berger RMF, Bartelds B. Bossers GPL, et al. J Thorac Cardiovasc Surg. 2022 Dec;164(6):e493-e510. doi: 10.1016/j.jtcvs.2021.10.045. Epub 2021 Nov 3. J Thorac Cardiovasc Surg. 2022. PMID: 34922752 Free article.
15 results