Paras N - Search Results

1

A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons.

Kim GJ, Mo H, Liu H, Wu Z, Chen S, Zheng J, Zhao X, Nucum D, Shortland J, Peng L, Elepano M, Tang B, Olson S, Paras N, Li H, Renslo AR, Arkin MR, Huang B, Lu B, Sirota M, Guo S. Kim GJ, et al. Among authors: paras n. Elife. 2021 Sep 22;10:e69795. doi: 10.7554/eLife.69795. Elife. 2021. PMID: 34550070 Free PMC article.

2

Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism.

O'Brien CJ, Droege DG, Jiu AY, Gandhi SS, Paras NA, Olson SH, Conrad J. O'Brien CJ, et al. J Org Chem. 2018 Aug 17;83(16):8926-8935. doi: 10.1021/acs.joc.8b01146. Epub 2018 Jul 6. J Org Chem. 2018. PMID: 29940725 Free PMC article.

3

Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.

Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. Grandjean JM, et al. ACS Med Chem Lett. 2020 Jan 30;11(2):127-132. doi: 10.1021/acsmedchemlett.9b00480. eCollection 2020 Feb 13. ACS Med Chem Lett. 2020. PMID: 32071678 Free PMC article.

4

Selectivity in the Addition of Electron Deficient Radicals to the C2 Position of Indoles.

Li Y, Vaz RJ, Olson SH, Munson M, Paras NA, Conrad J. Li Y, et al. Among authors: paras na. European J Org Chem. 2020 Sep 30;2020(36):5828-5832. doi: 10.1002/ejoc.201901784. Epub 2020 Aug 18. European J Org Chem. 2020. PMID: 33692651 Free PMC article.

5

Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent.

Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J. Nguyen TH, et al. Among authors: paras na. Org Lett. 2021 May 21;23(10):3823-3827. doi: 10.1021/acs.orglett.1c00871. Epub 2021 Apr 30. Org Lett. 2021. PMID: 33929208

6

Expanding spectrum of prion diseases.

Ayers JI, Paras NA, Prusiner SB. Ayers JI, et al. Among authors: paras na. Emerg Top Life Sci. 2020 Sep 8;4(2):155-167. doi: 10.1042/ETLS20200037. Emerg Top Life Sci. 2020. PMID: 32803268 Free article. Review.

7

Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy.

Ayers JI, Lee J, Monteiro O, Woerman AL, Lazar AA, Condello C, Paras NA, Prusiner SB. Ayers JI, et al. Among authors: paras na. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2113489119. doi: 10.1073/pnas.2113489119. Proc Natl Acad Sci U S A. 2022. PMID: 35115402 Free PMC article.

8

Cryo-EM structure of a novel α-synuclein filament subtype from multiple system atrophy.

Yan NL, Candido F, Tse E, Melo AA, Prusiner SB, Mordes DA, Southworth DR, Paras NA, Merz GE. Yan NL, et al. Among authors: paras na. FEBS Lett. 2025 Jan;599(1):33-40. doi: 10.1002/1873-3468.15048. Epub 2024 Nov 7. FEBS Lett. 2025. PMID: 39511911 Free PMC article.

9

Convenient route to secondary sulfinates: application to the stereospecific synthesis of α-C-chiral sulfonamides.

Johnson MG, Gribble MW Jr, Houze JB, Paras NA. Johnson MG, et al. Org Lett. 2014 Dec 5;16(23):6248-51. doi: 10.1021/ol503208z. Epub 2014 Nov 21. Org Lett. 2014. PMID: 25415837

10

Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles.

Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J. Lozano C, et al. Among authors: paras na. ACS Omega. 2021 Mar 31;6(14):9804-9812. doi: 10.1021/acsomega.1c00458. eCollection 2021 Apr 13. ACS Omega. 2021. PMID: 33869960 Free PMC article.

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