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STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma.
Morelli AP, Tortelli TC Jr, Mancini MCS, Pavan ICB, Silva LGS, Severino MB, Granato DC, Pestana NF, Ponte LGS, Peruca GF, Pauletti BA, Dos Santos DFG Jr, de Moura LP, Bezerra RMN, Leme AFP, Chammas R, Simabuco FM. Morelli AP, et al. Among authors: chammas r. Neoplasia. 2021 Sep 17;23(10):1048-1058. doi: 10.1016/j.neo.2021.08.003. Online ahead of print. Neoplasia. 2021. PMID: 34543857 Free PMC article.
Emerging targets for combination therapy in melanomas.
Saito Rde F, Tortelli TC Jr, Jacomassi MD, Otake AH, Chammas R. Saito Rde F, et al. Among authors: chammas r. FEBS Lett. 2015 Nov 14;589(22):3438-48. doi: 10.1016/j.febslet.2015.09.022. Epub 2015 Oct 6. FEBS Lett. 2015. PMID: 26450371 Free article. Review.
Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death.
Tortelli TC Junior, de Godoy LMF, de Souza GA, Bonatto D, Otake AH, de Freitas Saito R, Rosa JC, Greene LJ, Chammas R. Tortelli TC Junior, et al. Among authors: chammas r. Oncotarget. 2017 Jun 27;8(26):43114-43129. doi: 10.18632/oncotarget.17810. Oncotarget. 2017. PMID: 28562344 Free PMC article.
Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways.
Morelli AP, Tortelli TC Jr, Pavan ICB, Silva FR, Granato DC, Peruca GF, Pauletti BA, Domingues RR, Bezerra RMN, De Moura LP, Paes Leme AF, Chammas R, Simabuco FM. Morelli AP, et al. Among authors: chammas r. Int J Oncol. 2021 Jun;58(6):28. doi: 10.3892/ijo.2021.5208. Epub 2021 Apr 13. Int J Oncol. 2021. PMID: 33846781 Free PMC article.
Metformin-induced chemosensitization to cisplatin depends on P53 status and is inhibited by Jarid1b overexpression in non-small cell lung cancer cells.
Tortelli TC, Tamura RE, de Souza Junqueira M, da Silva Mororó J, Bustos SO, Natalino RJM, Russell S, Désaubry L, Strauss BE, Chammas R. Tortelli TC, et al. Among authors: chammas r. Aging (Albany NY). 2021 Sep 16;13(18):21914-21940. doi: 10.18632/aging.203528. Epub 2021 Sep 16. Aging (Albany NY). 2021. PMID: 34528900 Free PMC article.
Melanocyte transformation associated with substrate adhesion impediment.
Oba-Shinjo SM, Correa M, Ricca TI, Molognoni F, Pinhal MA, Neves IA, Marie SK, Sampaio LO, Nader HB, Chammas R, Jasiulionis MG. Oba-Shinjo SM, et al. Among authors: chammas r. Neoplasia. 2006 Mar;8(3):231-41. doi: 10.1593/neo.05781. Neoplasia. 2006. PMID: 16611417 Free PMC article.
261 results