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Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.
Taschler U, Radner FP, Heier C, Schreiber R, Schweiger M, Schoiswohl G, Preiss-Landl K, Jaeger D, Reiter B, Koefeler HC, Wojciechowski J, Theussl C, Penninger JM, Lass A, Haemmerle G, Zechner R, Zimmermann R. Taschler U, et al. Among authors: heier c. J Biol Chem. 2011 May 20;286(20):17467-77. doi: 10.1074/jbc.M110.215434. Epub 2011 Mar 23. J Biol Chem. 2011. PMID: 21454566 Free PMC article.
Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.
Pollak NM, Schweiger M, Jaeger D, Kolb D, Kumari M, Schreiber R, Kolleritsch S, Markolin P, Grabner GF, Heier C, Zierler KA, Rülicke T, Zimmermann R, Lass A, Zechner R, Haemmerle G. Pollak NM, et al. Among authors: heier c. J Lipid Res. 2013 Apr;54(4):1092-102. doi: 10.1194/jlr.M034710. Epub 2013 Jan 23. J Lipid Res. 2013. PMID: 23345410 Free PMC article.
Development of small-molecule inhibitors targeting adipose triglyceride lipase.
Mayer N, Schweiger M, Romauch M, Grabner GF, Eichmann TO, Fuchs E, Ivkovic J, Heier C, Mrak I, Lass A, Höfler G, Fledelius C, Zechner R, Zimmermann R, Breinbauer R. Mayer N, et al. Among authors: heier c. Nat Chem Biol. 2013 Dec;9(12):785-7. doi: 10.1038/nchembio.1359. Epub 2013 Oct 6. Nat Chem Biol. 2013. PMID: 24096302 Free PMC article.
Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.
Nagy HM, Paar M, Heier C, Moustafa T, Hofer P, Haemmerle G, Lass A, Zechner R, Oberer M, Zimmermann R. Nagy HM, et al. Among authors: heier c. Biochim Biophys Acta. 2014 Apr 4;1841(4):588-94. doi: 10.1016/j.bbalip.2014.01.005. Epub 2014 Jan 16. Biochim Biophys Acta. 2014. PMID: 24440819 Free PMC article.
Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion.
Mattijssen F, Georgiadi A, Andasarie T, Szalowska E, Zota A, Krones-Herzig A, Heier C, Ratman D, De Bosscher K, Qi L, Zechner R, Herzig S, Kersten S. Mattijssen F, et al. Among authors: heier c. J Biol Chem. 2014 Jul 11;289(28):19279-93. doi: 10.1074/jbc.M114.570044. Epub 2014 May 29. J Biol Chem. 2014. PMID: 24876382 Free PMC article.
78 results