Nicholas RA - Search Results

1

Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3-β4 loop to favor a low-affinity drug-binding state.

Fenton BA, Tomberg J, Sciandra CA, Nicholas RA, Davies C, Zhou P. Fenton BA, et al. Among authors: nicholas ra. J Biol Chem. 2021 Oct;297(4):101188. doi: 10.1016/j.jbc.2021.101188. Epub 2021 Sep 13. J Biol Chem. 2021. PMID: 34529975 Free PMC article.

2

Substitution of lysine 213 with arginine in penicillin-binding protein 5 of Escherichia coli abolishes D-alanine carboxypeptidase activity without affecting penicillin binding.

Malhotra KT, Nicholas RA. Malhotra KT, et al. Among authors: nicholas ra. J Biol Chem. 1992 Jun 5;267(16):11386-91. J Biol Chem. 1992. PMID: 1597468 Free article.

3

Expression and purification of a soluble form of penicillin-binding protein 2 from both penicillin-susceptible and penicillin-resistant Neisseria gonorrhoeae.

Schultz DE, Spratt BG, Nicholas RA. Schultz DE, et al. Among authors: nicholas ra. Protein Expr Purif. 1991 Oct-Dec;2(5-6):339-49. doi: 10.1016/1046-5928(91)90092-w. Protein Expr Purif. 1991. PMID: 1821807

4

Site-directed mutants of a soluble form of penicillin-binding protein 5 from Escherichia coli and their catalytic properties.

Nicholas RA, Strominger JL. Nicholas RA, et al. J Biol Chem. 1988 Feb 5;263(4):2034-40. J Biol Chem. 1988. PMID: 3276680 Free article.

5

Penicillin-binding protein 1B from Escherichia coli contains a membrane association site in addition to its transmembrane anchor.

Nicholas RA, Lamson DR, Schultz DE. Nicholas RA, et al. J Biol Chem. 1993 Mar 15;268(8):5632-41. J Biol Chem. 1993. PMID: 8449926 Free article.

6

Random mutagenesis of the sheep Na,K-ATPase alpha1 subunit generating the ouabain-resistant mutant L793P.

Burns EL, Nicholas RA, Price EM. Burns EL, et al. Among authors: nicholas ra. J Biol Chem. 1996 Jul 5;271(27):15879-83. doi: 10.1074/jbc.271.27.15879. J Biol Chem. 1996. PMID: 8663108 Free article.

7

Cloning and characterization of the ponA gene encoding penicillin-binding protein 1 from Neisseria gonorrhoeae and Neisseria meningitidis.

Ropp PA, Nicholas RA. Ropp PA, et al. Among authors: nicholas ra. J Bacteriol. 1997 Apr;179(8):2783-7. doi: 10.1128/jb.179.8.2783-2787.1997. J Bacteriol. 1997. PMID: 9098083 Free PMC article.

8

Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution.

Davies C, White SW, Nicholas RA. Davies C, et al. Among authors: nicholas ra. J Biol Chem. 2001 Jan 5;276(1):616-23. doi: 10.1074/jbc.M004471200. J Biol Chem. 2001. PMID: 10967102 Free article.

9

Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae.

Ropp PA, Hu M, Olesky M, Nicholas RA. Ropp PA, et al. Among authors: nicholas ra. Antimicrob Agents Chemother. 2002 Mar;46(3):769-77. doi: 10.1128/AAC.46.3.769-777.2002. Antimicrob Agents Chemother. 2002. PMID: 11850260 Free PMC article.

10

pH, inhibitor, and substrate specificity studies on Escherichia coli penicillin-binding protein 5.

Stefanova ME, Davies C, Nicholas RA, Gutheil WG. Stefanova ME, et al. Among authors: nicholas ra. Biochim Biophys Acta. 2002 Jun 3;1597(2):292-300. doi: 10.1016/s0167-4838(02)00311-4. Biochim Biophys Acta. 2002. PMID: 12044907

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