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Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner.
Gupta VK, Scheunemann L, Eisenberg T, Mertel S, Bhukel A, Koemans TS, Kramer JM, Liu KS, Schroeder S, Stunnenberg HG, Sinner F, Magnes C, Pieber TR, Dipt S, Fiala A, Schenck A, Schwaerzel M, Madeo F, Sigrist SJ. Gupta VK, et al. Among authors: sigrist sj. Nat Neurosci. 2013 Oct;16(10):1453-60. doi: 10.1038/nn.3512. Epub 2013 Sep 1. Nat Neurosci. 2013. PMID: 23995066
A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
Siebert M, Böhme MA, Driller JH, Babikir H, Mampell MM, Rey U, Ramesh N, Matkovic T, Holton N, Reddy-Alla S, Göttfert F, Kamin D, Quentin C, Klinedinst S, Andlauer TF, Hell SW, Collins CA, Wahl MC, Loll B, Sigrist SJ. Siebert M, et al. Among authors: sigrist sj. Elife. 2015 Aug 14;4:e06935. doi: 10.7554/eLife.06935. Elife. 2015. PMID: 26274777 Free PMC article.
Spermidine-triggered autophagy ameliorates memory during aging.
Sigrist SJ, Carmona-Gutierrez D, Gupta VK, Bhukel A, Mertel S, Eisenberg T, Madeo F. Sigrist SJ, et al. Autophagy. 2014 Jan;10(1):178-9. doi: 10.4161/auto.26918. Epub 2013 Nov 15. Autophagy. 2014. PMID: 24262970 Free PMC article.
Drep-2 is a novel synaptic protein important for learning and memory.
Andlauer TF, Scholz-Kornehl S, Tian R, Kirchner M, Babikir HA, Depner H, Loll B, Quentin C, Gupta VK, Holt MG, Dipt S, Cressy M, Wahl MC, Fiala A, Selbach M, Schwärzel M, Sigrist SJ. Andlauer TF, et al. Among authors: sigrist sj. Elife. 2014 Nov 13;3:e03895. doi: 10.7554/eLife.03895. Elife. 2014. PMID: 25392983 Free PMC article.
271 results