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Page 1
The HIV latency reversing agent HODHBt inhibits the phosphatases PTPN1 and PTPN2.
Howard JN, Zaikos TD, Levinger C, Rivera E, McMahon EK, Holmberg CS, Terao J, Sanz M, Copertino DC Jr, Wang W, Soriano-Sarabia N, Jones RB, Bosque A. Howard JN, et al. Among authors: copertino dc jr. JCI Insight. 2024 Aug 8;9(18):e179680. doi: 10.1172/jci.insight.179680. JCI Insight. 2024. PMID: 39115957 Free PMC article.
HIV-1 subtype A1, D, and recombinant proviral genome landscapes during long-term suppressive therapy.
Lee GQ, Khadka P, Gowanlock SN, Copertino DC Jr, Duncan MC, Omondi FH, Kinloch NN, Kasule J, Kityamuweesi T, Buule P, Jamiru S, Tomusange S, Anok A, Chen Z, Jones RB, Galiwango RM, Reynolds SJ, Quinn TC, Brumme ZL, Redd AD, Prodger JL. Lee GQ, et al. Among authors: copertino dc jr. Nat Commun. 2024 Jul 2;15(1):5480. doi: 10.1038/s41467-024-48985-9. Nat Commun. 2024. PMID: 38956017 Free PMC article.
Immunogenicity of COVID-19 vaccines and their effect on HIV reservoir in older people with HIV.
Matveev VA, Mihelic EZ, Benko E, Budylowski P, Grocott S, Lee T, Korosec CS, Colwill K, Stephenson H, Law R, Ward LA, Sheikh-Mohamed S, Mailhot G, Delgado-Brand M, Pasculescu A, Wang JH, Qi F, Tursun T, Kardava L, Chau S, Samaan P, Imran A, Copertino DC Jr, Chao G, Choi Y, Reinhard RJ, Kaul R, Heffernan JM, Jones RB, Chun TW, Moir S, Singer J, Gommerman J, Gingras AC, Kovacs C, Ostrowski M. Matveev VA, et al. Among authors: copertino dc jr. iScience. 2023 Sep 14;26(10):107915. doi: 10.1016/j.isci.2023.107915. eCollection 2023 Oct 20. iScience. 2023. PMID: 37790281 Free PMC article.
Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence: the randomized phase 2a TITAN trial.
Gunst JD, Højen JF, Pahus MH, Rosás-Umbert M, Stiksrud B, McMahon JH, Denton PW, Nielsen H, Johansen IS, Benfield T, Leth S, Gerstoft J, Østergaard L, Schleimann MH, Olesen R, Støvring H, Vibholm L, Weis N, Dyrhol-Riise AM, Pedersen KBH, Lau JSY, Copertino DC Jr, Linden N, Huynh TT, Ramos V, Jones RB, Lewin SR, Tolstrup M, Rasmussen TA, Nussenzweig MC, Caskey M, Reikvam DH, Søgaard OS. Gunst JD, et al. Among authors: copertino dc jr. Nat Med. 2023 Oct;29(10):2547-2558. doi: 10.1038/s41591-023-02547-6. Epub 2023 Sep 11. Nat Med. 2023. PMID: 37696935 Free PMC article. Clinical Trial.
The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells.
Copertino DC Jr, Holmberg CS, Weiler J, Ward AR, Howard JN, Levinger C, Pang AP, Corley MJ, Dündar F, Zumbo P, Betel D, Gandhi RT, McMahon DK, Bosch RJ, Linden N, Macatangay BJ, Cyktor JC, Eron JJ, Mellors JW, Kovacs C, Benko E, Bosque A, Jones RB; AIDS Clinical Trials Group (ACTG) A5321 Team. Copertino DC Jr, et al. JCI Insight. 2023 Sep 22;8(18):e169028. doi: 10.1172/jci.insight.169028. JCI Insight. 2023. PMID: 37581929 Free PMC article.
Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV.
Matveev VA, Mihelic EZ, Benko E, Budylowski P, Grocott S, Lee T, Korosec CS, Colwill K, Stephenson H, Law R, Ward LA, Sheikh-Mohamed S, Mailhot G, Delgado-Brand M, Pasculescu A, Wang JH, Qi F, Tursun T, Kardava L, Chau S, Samaan P, Imran A, Copertino DC Jr, Chao G, Choi Y, Reinhard RJ, Kaul R, Heffernan JM, Jones RB, Chun TW, Moir S, Singer J, Gommerman J, Gingras AC, Kovacs C, Ostrowski M. Matveev VA, et al. Among authors: copertino dc jr. bioRxiv [Preprint]. 2023 Jun 15:2023.06.14.544834. doi: 10.1101/2023.06.14.544834. bioRxiv. 2023. Update in: iScience. 2023 Sep 14;26(10):107915. doi: 10.1016/j.isci.2023.107915 PMID: 37502977 Free PMC article. Updated. Preprint.
Restriction Factor Expression in Vertically Infected Children Living With HIV-1.
Bortlik M, Copertino DC Jr, Brailey PM, Beckerle GA, Ormsby CE, Rosenberg MG, Wiznia AA, Raposo RAS, Nixon DF, de Mulder Rougvie M. Bortlik M, et al. Among authors: copertino dc jr. Pediatr Infect Dis J. 2021 Feb 1;40(2):144-146. doi: 10.1097/INF.0000000000002924. Pediatr Infect Dis J. 2021. PMID: 33395209