Leclercq G - Search Results

1

Analogues of tamoxifen: the role of the basic side-chain. Applications of a whole-cell oestrogen-receptor binding assay to N-oxides and quaternary salts.

Jarman M, Leung OT, Leclercq G, Devleeschouwer N, Stoessel S, Coombes RC, Skilton RA. Jarman M, et al. Among authors: leclercq g. Anticancer Drug Des. 1986 Nov;1(3):259-68. Anticancer Drug Des. 1986. PMID: 3450298

2

Metabolism of tamoxifen by isolated rat hepatocytes. Identification of the glucuronide of 4-hydroxytamoxifen.

McCague R, Parr IB, Leclercq G, Leung OT, Jarman M. McCague R, et al. Among authors: leclercq g. Biochem Pharmacol. 1990 May 1;39(9):1459-65. doi: 10.1016/0006-2952(90)90427-m. Biochem Pharmacol. 1990. PMID: 2334445

3

Non-isomerisable antiestrogens related to tamoxifen.

McCague R, Jarman M, Leung OT, Foster AB, Leclercq G, Stoessel S. McCague R, et al. Among authors: leclercq g. J Steroid Biochem. 1988 Oct;31(4B):545-7. doi: 10.1016/0022-4731(88)90005-2. J Steroid Biochem. 1988. PMID: 3199805

4

Modification of the basic side chain in tamoxifen: effects on microsomal metabolism and in vitro biological activity.

Foster AB, McCague R, Seago A, Leclercq G, Stoessel S, Roy F. Foster AB, et al. Among authors: leclercq g. Anticancer Drug Des. 1986 Nov;1(3):245-57. Anticancer Drug Des. 1986. PMID: 3450297

5

Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent.

McCague R, Leclercq G, Legros N, Goodman J, Blackburn GM, Jarman M, Foster AB. McCague R, et al. Among authors: leclercq g. J Med Chem. 1989 Dec;32(12):2527-33. doi: 10.1021/jm00132a006. J Med Chem. 1989. PMID: 2585441

6

Hydroxy derivatives of tamoxifen.

Foster AB, Jarman M, Leung OT, McCague R, Leclercq G, Devleeschouwer N. Foster AB, et al. Among authors: leclercq g. J Med Chem. 1985 Oct;28(10):1491-7. doi: 10.1021/jm00148a020. J Med Chem. 1985. PMID: 4045924

7

Antagonism of estrogen receptor and calmodulin association by antiestrogens is not dependent on an interaction with calmodulin.

Rowlands MG, Grimshaw R, Jarman M, Bouhoute A, Leclercq G. Rowlands MG, et al. Among authors: leclercq g. Biochem Pharmacol. 1997 Jan 24;53(2):241-4. doi: 10.1016/s0006-2952(96)00603-x. Biochem Pharmacol. 1997. PMID: 9037257

8

Competitive binding assay for estrogen receptor in monolayer culture: measure of receptor activation potency.

Stoessel S, Leclercq G. Stoessel S, et al. Among authors: leclercq g. J Steroid Biochem. 1986 Nov;25(5A):677-82. doi: 10.1016/0022-4731(86)90010-5. J Steroid Biochem. 1986. PMID: 2432356

9

Metabolism of tamoxifen by isolated rat hepatocytes. Identification of 1-[4-(2-hydroxyethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenyl-1-butene and the dependence of N-oxidation on oxygen availability.

Parr IB, McCague R, Leclercq G, Stoessel S. Parr IB, et al. Among authors: leclercq g. Biochem Pharmacol. 1987 May 1;36(9):1513-9. doi: 10.1016/0006-2952(87)90119-5. Biochem Pharmacol. 1987. PMID: 3579987

10

Synthesis and estrogen receptor binding of 6,7-dihydro-8-phenyl-9-[4-[2-(dimethylamino)ethoxy] phenyl]-5H-benzocycloheptene, a nonisomerizable analogue of tamoxifen. X-ray crystallographic studies.

McCague R, Kuroda R, Leclercq G, Stoessel S. McCague R, et al. Among authors: leclercq g. J Med Chem. 1986 Oct;29(10):2053-9. doi: 10.1021/jm00160a044. J Med Chem. 1986. PMID: 3761324

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