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Page 1
Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis.
Gluais-Dagorn P, Foretz M, Steinberg GR, Batchuluun B, Zawistowska-Deniziak A, Lambooij JM, Guigas B, Carling D, Monternier PA, Moller DE, Bolze S, Hallakou-Bozec S. Gluais-Dagorn P, et al. Among authors: hallakou bozec s. Hepatol Commun. 2022 Jan;6(1):101-119. doi: 10.1002/hep4.1799. Epub 2021 Sep 7. Hepatol Commun. 2022. PMID: 34494384 Free PMC article.
Short-and long-term administration of imeglimin counters cardiorenal dysfunction in a rat model of metabolic syndrome.
Lachaux M, Soulié M, Hamzaoui M, Bailly A, Nicol L, Rémy-Jouet I, Renet S, Vendeville C, Gluais-Dagorn P, Hallakou-Bozec S, Monteil C, Richard V, Mulder P. Lachaux M, et al. Endocrinol Diabetes Metab. 2020 Apr 16;3(3):e00128. doi: 10.1002/edm2.128. eCollection 2020 Jul. Endocrinol Diabetes Metab. 2020. PMID: 32704553 Free PMC article.
Imeglimin preserves islet β-cell mass in Type 2 diabetic ZDF rats.
Hallakou-Bozec S, Kergoat M, Moller DE, Bolze S. Hallakou-Bozec S, et al. Endocrinol Diabetes Metab. 2020 Nov 7;4(2):e00193. doi: 10.1002/edm2.193. eCollection 2021 Apr. Endocrinol Diabetes Metab. 2020. PMID: 33855202 Free PMC article.
Efficacy and safety of PXL770, a direct AMP kinase activator, for the treatment of non-alcoholic fatty liver disease (STAMP-NAFLD): a randomised, double-blind, placebo-controlled, phase 2a study.
Cusi K, Alkhouri N, Harrison SA, Fouqueray P, Moller DE, Hallakou-Bozec S, Bolze S, Grouin JM, Jeannin Megnien S, Dubourg J, Ratziu V. Cusi K, et al. Among authors: hallakou bozec s. Lancet Gastroenterol Hepatol. 2021 Nov;6(11):889-902. doi: 10.1016/S2468-1253(21)00300-9. Epub 2021 Sep 22. Lancet Gastroenterol Hepatol. 2021. PMID: 34560015 Clinical Trial.
19 results