Li X - Search Results

1

Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations.

Dong X, Qi R, Qiao Q, Li X, Li F, Wan J, Zhang Q, Wei G. Dong X, et al. Among authors: li f, li x. Phys Chem Chem Phys. 2021 Sep 22;23(36):20406-20418. doi: 10.1039/d1cp02651h. Phys Chem Chem Phys. 2021. PMID: 34494046

2

The distinct structural preferences of tau protein repeat domains.

Li X , Dong X , Wei G , Margittai M , Nussinov R , Ma B . Li X , et al. Chem Commun (Camb). 2018 May 31;54(45):5700-5703. doi: 10.1039/c8cc01263f. Chem Commun (Camb). 2018. PMID: 29774342 Free PMC article.

3

Mechanistic insight into E22Q-mutation-induced antiparallel-to-parallel β-sheet transition of Aβ_16-22 fibrils: an all-atom simulation study.

Li X, Lei J, Qi R, Xie L, Wei G. Li X, et al. Phys Chem Chem Phys. 2019 Jul 17;21(28):15686-15694. doi: 10.1039/c9cp02561h. Phys Chem Chem Phys. 2019. PMID: 31271401

4

Common cancer mutations R175H and R273H drive the p53 DNA-binding domain towards aggregation-prone conformations.

Li L , Li X , Tang Y , Lao Z , Lei J , Wei G . Li L , et al. Among authors: li x. Phys Chem Chem Phys. 2020 May 7;22(17):9225-9232. doi: 10.1039/c9cp06671c. Epub 2020 Apr 20. Phys Chem Chem Phys. 2020. PMID: 32307496

5

Mechanistic Insights into the Co-Aggregation of Aβ and hIAPP: An All-Atom Molecular Dynamic Study.

Li X, Lao Z, Zou Y, Dong X, Li L, Wei G. Li X, et al. Among authors: li l. J Phys Chem B. 2021 Mar 4;125(8):2050-2060. doi: 10.1021/acs.jpcb.0c11132. Epub 2021 Feb 22. J Phys Chem B. 2021. PMID: 33616398

6

Molecular insights into the binding variance of the SARS-CoV-2 spike with human, cat and dog ACE2 proteins.

Zang Y , Li X , Zhao Y , Wang H , Hao D , Zhang L , Yang Z , Yuan X , Zhang S . Zang Y , et al. Among authors: li x. Phys Chem Chem Phys. 2021 Jun 28;23(24):13752-13759. doi: 10.1039/d1cp01611c. Epub 2021 Jun 15. Phys Chem Chem Phys. 2021. PMID: 34132301

7

A Comprehensive Insight into the Mechanisms of Dopamine in Disrupting Aβ Protofibrils and Inhibiting Aβ Aggregation.

Chen Y, Li X, Zhan C, Lao Z, Li F, Dong X, Wei G. Chen Y, et al. Among authors: li f, li x. ACS Chem Neurosci. 2021 Nov 3;12(21):4007-4019. doi: 10.1021/acschemneuro.1c00306. Epub 2021 Sep 2. ACS Chem Neurosci. 2021. PMID: 34472835

8

Deciphering the mechanisms of HPV E6 mutations in the destabilization of E6/E6AP/p53 complex.

Li L, Dong X, Tang Y, Lao Z, Li X, Lei J, Wei G. Li L, et al. Among authors: li x. Biophys J. 2022 May 3;121(9):1704-1714. doi: 10.1016/j.bpj.2022.03.030. Epub 2022 Mar 29. Biophys J. 2022. PMID: 35364103 Free PMC article.

9

TAB1 binding induced p38α conformation change: an accelerated molecular dynamics simulation study.

Zang Y, Wang H, Kang Y, Zhang J, Li X, Zhang L, Yang Z, Zhang S. Zang Y, et al. Among authors: li x. Phys Chem Chem Phys. 2022 May 4;24(17):10506-10513. doi: 10.1039/d2cp00144f. Phys Chem Chem Phys. 2022. PMID: 35441632

10

ALS-associated A315E and A315pT variants exhibit distinct mechanisms in inducing irreversible aggregation of TDP-43_312-317 peptides.

Liu X, Lao Z, Li X, Dong X, Wei G. Liu X, et al. Among authors: li x. Phys Chem Chem Phys. 2022 Jul 6;24(26):16263-16273. doi: 10.1039/d2cp01625g. Phys Chem Chem Phys. 2022. PMID: 35758309

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