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Page 1
The cardiovascular effects of amodiaquine and structurally related antimalarials: An individual patient data meta-analysis.
Chan XHS, Haeusler IL, Win YN, Pike J, Hanboonkunupakarn B, Hanafiah M, Lee SJ, Djimdé A, Fanello CI, Kiechel JR, Lacerda MV, Ogutu B, Onyamboko MA, Siqueira AM, Ashley EA, Taylor WR, White NJ. Chan XHS, et al. Among authors: kiechel jr. PLoS Med. 2021 Sep 7;18(9):e1003766. doi: 10.1371/journal.pmed.1003766. eCollection 2021 Sep. PLoS Med. 2021. PMID: 34492005 Free PMC article.
Population pharmacokinetics of artesunate and amodiaquine in African children.
Stepniewska K, Taylor W, Sirima SB, Ouedraogo EB, Ouedraogo A, Gansané A, Simpson JA, Morgan CC, White NJ, Kiechel JR. Stepniewska K, et al. Among authors: kiechel jr. Malar J. 2009 Aug 20;8:200. doi: 10.1186/1475-2875-8-200. Malar J. 2009. PMID: 19691851 Free PMC article. Clinical Trial.
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data.
WWARN Artemisinin based Combination Therapy (ACT) Africa Baseline Study Group; Dahal P, d'Alessandro U, Dorsey G, Guerin PJ, Nsanzabana C, Price RN, Sibley CH, Stepniewska K, Talisuna AO. WWARN Artemisinin based Combination Therapy (ACT) Africa Baseline Study Group, et al. BMC Med. 2015 Sep 7;13:212. doi: 10.1186/s12916-015-0445-x. BMC Med. 2015. PMID: 26343145 Free PMC article. Review.
Cardiovascular concentration-effect relationships of amodiaquine and its metabolite desethylamodiaquine: Clinical and preclinical studies.
Chan XHS, Chotsiri P, Capel RA, Pike J, Hanboonkunupakarn B, Lee SJ, Hanafiah M, Win YN, Cremer MA, Kiechel JR, Ogutu B, Taylor WRJ, Burton RB, Tarning J, White NJ. Chan XHS, et al. Among authors: kiechel jr. Br J Clin Pharmacol. 2023 Mar;89(3):1176-1186. doi: 10.1111/bcp.15569. Epub 2022 Nov 8. Br J Clin Pharmacol. 2023. PMID: 36256474 Free PMC article.
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.
WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group; Adjuik MA, Allan R, Anvikar AR, Ashley EA, Ba MS, Barennes H, Barnes KI, Bassat Q, Baudin E, Björkman A, Bompart F, Bonnet M, Borrmann S, Brasseur P, Bukirwa H, Checchi F, Cot M, Dahal P, D'Alessandro U, Deloron P, Desai M, Diap G, Djimde AA, Dorsey G, Doumbo OK, Espié E, Etard JF, Fanello CI, Faucher JF, Faye B, Flegg JA, Gaye O, Gething PW, González R, Grandesso F, Guerin PJ, Guthmann JP, Hamour S, Hasugian AR, Hay SI, Humphreys GS, Jullien V, Juma E, Kamya MR, Karema C, Kiechel JR, Kremsner PG, Krishna S, Lameyre V, Ibrahim LM, Lee SJ, Lell B, Mårtensson A, Massougbodji A, Menan H, Ménard D, Menéndez C, Meremikwu M, Moreira C, Nabasumba C, Nambozi M, Ndiaye JL, Nikiema F, Nsanzabana C, Ntoumi F, Ogutu BR, Olliaro P, Osorio L, Ouédraogo JB, Penali LK, Pene M, Pinoges L, Piola P, Price RN, Roper C, Rosenthal PJ, Rwagacondo CE, Same-Ekobo A, Schramm B, Seck A, Sharma B, Sibley CH, Sinou V, Sirima SB, Smith JJ, Smithuis F, Somé FA, Sow D, Staedke SG, Stepniewska K, Swarthout TD, Sylla K, Talisuna AO, Tarning J, Taylor WR, Temu EA, Thwing JI, Tjitra E, Tine RC, Tinto H, Vaillant MT, Valecha N, Van den Broek … See abstract for full author list ➔ WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group, et al. Among authors: kiechel jr. BMC Med. 2015 Mar 31;13:66. doi: 10.1186/s12916-015-0301-z. BMC Med. 2015. PMID: 25888957 Free PMC article.
The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network.
Hossain MS, Commons RJ, Douglas NM, Thriemer K, Alemayehu BH, Amaratunga C, Anvikar AR, Ashley EA, Asih PBS, Carrara VI, Lon C, D'Alessandro U, Davis TME, Dondorp AM, Edstein MD, Fairhurst RM, Ferreira MU, Hwang J, Janssens B, Karunajeewa H, Kiechel JR, Ladeia-Andrade S, Laman M, Mayxay M, McGready R, Moore BR, Mueller I, Newton PN, Thuy-Nhien NT, Noedl H, Nosten F, Phyo AP, Poespoprodjo JR, Saunders DL, Smithuis F, Spring MD, Stepniewska K, Suon S, Suputtamongkol Y, Syafruddin D, Tran HT, Valecha N, Van Herp M, Van Vugt M, White NJ, Guerin PJ, Simpson JA, Price RN. Hossain MS, et al. Among authors: kiechel jr. PLoS Med. 2020 Nov 19;17(11):e1003393. doi: 10.1371/journal.pmed.1003393. eCollection 2020 Nov. PLoS Med. 2020. PMID: 33211712 Free PMC article.
Population pharmacokinetics and pharmacodynamic considerations of amodiaquine and desethylamodiaquine in Kenyan adults with uncomplicated malaria receiving artesunate-amodiaquine combination therapy.
Jullien V, Ogutu B, Juma E, Carn G, Obonyo C, Kiechel JR. Jullien V, et al. Among authors: kiechel jr. Antimicrob Agents Chemother. 2010 Jun;54(6):2611-7. doi: 10.1128/AAC.01496-09. Epub 2010 Apr 5. Antimicrob Agents Chemother. 2010. PMID: 20368402 Free PMC article. Clinical Trial.
71 results