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Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived dopaminergic neurons: Implications for Parkinson's disease.
Haynes JM, Sibuea SM, Aguiar AA, Li F, Ho JK, Pouton CW. Haynes JM, et al. Among authors: aguiar aa. PLoS One. 2021 Dec 23;16(12):e0261730. doi: 10.1371/journal.pone.0261730. eCollection 2021. PLoS One. 2021. PMID: 34941945 Free PMC article.
Safety, Efficacy and Pharmacokinetics of daily optimised doses of Rifampicin for the Treatment of Tuberculosis: A Systematic Review and Bayesian Network Meta-Analysis.
Espinosa-Pereiro J, Aguiar A, Nara E, Medina A, Molinas G, Tavares M, Tortola T, Ghimire S, Alfenaar JC, Sturkenboom MGG, Magis-Escurra C, Sánchez-Montalva A, Barros H, Duarte R. Espinosa-Pereiro J, et al. Among authors: aguiar a. Clin Infect Dis. 2025 Jan 10:ciaf003. doi: 10.1093/cid/ciaf003. Online ahead of print. Clin Infect Dis. 2025. PMID: 39792625
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
Xie SC, Tai CW, Morton CJ, Ma L, Huang SC, Wittlin S, Du Y, Hu Y, Dogovski C, Salimimarand M, Griffin R, England D, de la Cruz E, Deni I, Yeo T, Burkhard AY, Striepen J, Schindler KA, Crespo B, Gamo FJ, Khandokar Y, Hutton CA, Rabie T, Birkholtz LM, Famodimu MT, Delves MJ, Bolsher J, Koolen KMJ, van der Laak R, Aguiar ACC, Pereira DB, Guido RVC, Creek DJ, Fidock DA, Dick LR, Brand SL, Gould AE, Langston S, Griffin MDW, Tilley L. Xie SC, et al. Among authors: aguiar acc. PLoS Pathog. 2024 Dec 9;20(12):e1012429. doi: 10.1371/journal.ppat.1012429. eCollection 2024 Dec. PLoS Pathog. 2024. PMID: 39652589 Free PMC article.
843 results