Chen SX - Search Results

1

Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection.

Thirunavukarasu D, Cheng LY, Song P, Chen SX, Borad MJ, Kwong L, James P, Turner DJ, Zhang DY. Thirunavukarasu D, et al. Among authors: chen sx. Genome Biol. 2021 Sep 6;22(1):227. doi: 10.1186/s13059-021-02449-1. Genome Biol. 2021. PMID: 34482832 Free PMC article.

2

Optimizing the specificity of nucleic acid hybridization.

Zhang DY, Chen SX, Yin P. Zhang DY, et al. Among authors: chen sx. Nat Chem. 2012 Jan 22;4(3):208-14. doi: 10.1038/nchem.1246. Nat Chem. 2012. PMID: 22354435 Free PMC article.

3

Conditionally fluorescent molecular probes for detecting single base changes in double-stranded DNA.

Chen SX, Zhang DY, Seelig G. Chen SX, et al. Nat Chem. 2013 Sep;5(9):782-9. doi: 10.1038/nchem.1713. Epub 2013 Jul 28. Nat Chem. 2013. PMID: 23965681 Free PMC article.

4

Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification.

Wu LR, Chen SX, Wu Y, Patel AA, Zhang DY. Wu LR, et al. Among authors: chen sx. Nat Biomed Eng. 2017;1:714-723. doi: 10.1038/s41551-017-0126-5. Epub 2017 Sep 4. Nat Biomed Eng. 2017. PMID: 29805844 Free PMC article.

5

Simultaneous and stoichiometric purification of hundreds of oligonucleotides.

Pinto A, Chen SX, Zhang DY. Pinto A, et al. Among authors: chen sx. Nat Commun. 2018 Jun 25;9(1):2467. doi: 10.1038/s41467-018-04870-w. Nat Commun. 2018. PMID: 29941961 Free PMC article.

6

Publisher Correction: Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification.

Wu LR, Chen SX, Wu Y, Patel AA, Zhang DY. Wu LR, et al. Among authors: chen sx. Nat Biomed Eng. 2017 Dec;1(12):1005. doi: 10.1038/s41551-017-0156-z. Nat Biomed Eng. 2017. PMID: 31015703

7

Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing.

Song P, Chen SX, Yan YH, Pinto A, Cheng LY, Dai P, Patel AA, Zhang DY. Song P, et al. Among authors: chen sx. Nat Biomed Eng. 2021 Jul;5(7):690-701. doi: 10.1038/s41551-021-00713-0. Epub 2021 May 3. Nat Biomed Eng. 2021. PMID: 33941896 Free PMC article.

8

Confirming putative variants at ≤ 5% allele frequency using allele enrichment and Sanger sequencing.

Yan YH, Chen SX, Cheng LY, Rodriguez AY, Tang R, Cabrera K, Zhang DY. Yan YH, et al. Among authors: chen sx. Sci Rep. 2021 Jun 2;11(1):11640. doi: 10.1038/s41598-021-91142-1. Sci Rep. 2021. PMID: 34079006 Free PMC article.

9

Calibration-free NGS quantitation of mutations below 0.01% VAF.

Dai P, Wu LR, Chen SX, Wang MX, Cheng LY, Zhang JX, Hao P, Yao W, Zarka J, Issa GC, Kwong L, Zhang DY. Dai P, et al. Among authors: chen sx. Nat Commun. 2021 Oct 21;12(1):6123. doi: 10.1038/s41467-021-26308-6. Nat Commun. 2021. PMID: 34675197 Free PMC article.

10

Ensemble of nucleic acid absolute quantitation modules for copy number variation detection and RNA profiling.

Wu LR, Dai P, Wang MX, Chen SX, Cohen EN, Jayachandran G, Zhang JX, Serrano AV, Xie NG, Ueno NT, Reuben JM, Barcenas CH, Zhang DY. Wu LR, et al. Among authors: chen sx. Nat Commun. 2022 Apr 4;13(1):1791. doi: 10.1038/s41467-022-29487-y. Nat Commun. 2022. PMID: 35379811 Free PMC article.

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