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Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis-associated colon cancer.
Ohnishi T, Hashizume C, Taniguchi M, Furumoto H, Han J, Gao R, Kinami S, Kosaka T, Okazaki T. Ohnishi T, et al. Among authors: okazaki t. FASEB J. 2017 Sep;31(9):3816-3830. doi: 10.1096/fj.201601225RR. Epub 2017 May 18. FASEB J. 2017. PMID: 28522594
Our results demonstrate that SMS2 deficiency inhibits DSS-induced colitis and subsequent colitis-associated colon cancer via inhibition of colon epithelial cell-mediated inflammation; therefore, inhibition of SMS2 may be a potential therapeutic target for human colitis and colore …
Our results demonstrate that SMS2 deficiency inhibits DSS-induced colitis and subsequent colitis-associated colon cancer via inhibition of c …
Sphingomyelin synthase 1-generated sphingomyelin plays an important role in transferrin trafficking and cell proliferation.
Shakor ABA, Taniguchi M, Kitatani K, Hashimoto M, Asano S, Hayashi A, Nomura K, Bielawski J, Bielawska A, Watanabe K, Kobayashi T, Igarashi Y, Umehara H, Takeya H, Okazaki T. Shakor ABA, et al. Among authors: okazaki t. J Biol Chem. 2011 Oct 14;286(41):36053-36062. doi: 10.1074/jbc.M111.228593. Epub 2011 Aug 19. J Biol Chem. 2011. PMID: 21856749 Free PMC article.
1,847 results