Rangarajan TM - Search Results

1

Recent Updates on Pyrazoline Derivatives as Promising Candidates for Neuropsychiatric and Neurodegenerative Disorders.

Rangarajan TM, Mathew B. Rangarajan TM, et al. Curr Top Med Chem. 2021;21(30):2695-2714. doi: 10.2174/1568026621999210902123132. Curr Top Med Chem. 2021. PMID: 34477522 Review.

2

Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease.

Reeta, Baek SC, Lee JP, Rangarajan TM, Ayushee, Singh RP, Singh M, Mangiatordi GF, Nicolotti O, Kim H, Mathew B. Reeta, et al. Among authors: rangarajan tm. CNS Neurol Disord Drug Targets. 2019;18(8):643-654. doi: 10.2174/1871527318666190906101326. CNS Neurol Disord Drug Targets. 2019. PMID: 31550216

3

Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.

Oh JM, Rangarajan TM, Chaudhary R, Singh RP, Singh M, Singh RP, Tondo AR, Gambacorta N, Nicolotti O, Mathew B, Kim H. Oh JM, et al. Among authors: rangarajan tm. Molecules. 2020 May 18;25(10):2356. doi: 10.3390/molecules25102356. Molecules. 2020. PMID: 32443652 Free PMC article.

4

(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors.

Palakkathondi A, Oh JM, Dev S, Rangarajan TM, Kaipakasseri S, Kavully FS, Gambacorta N, Nicolotti O, Kim H, Mathew B. Palakkathondi A, et al. Among authors: rangarajan tm. ACS Comb Sci. 2020 Nov 9;22(11):592-599. doi: 10.1021/acscombsci.0c00136. Epub 2020 Oct 13. ACS Comb Sci. 2020. PMID: 33047950

5

Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review.

Koyiparambath VP, Prayaga Rajappan K, Rangarajan TM, Al-Sehemi AG, Pannipara M, Bhaskar V, Nair AS, Sudevan ST, Kumar S, Mathew B. Koyiparambath VP, et al. Among authors: rangarajan tm. Chem Biol Drug Des. 2021 Oct;98(4):655-673. doi: 10.1111/cbdd.13919. Epub 2021 Jul 26. Chem Biol Drug Des. 2021. PMID: 34233082 Review.

6

Development of 2D, 3D-QSAR and Pharmacophore Modeling of Chalcones for the Inhibition of Monoamine Oxidase B.

Mathew B, Herrera-Acevedo C, Dev S, Rangarajan TM, Kuruniyan MS, Naseef PP, Scotti L, Scotti MT. Mathew B, et al. Among authors: rangarajan tm. Comb Chem High Throughput Screen. 2022;25(10):1731-1744. doi: 10.2174/1386207324666210816125738. Comb Chem High Throughput Screen. 2022. PMID: 34397324

7

Replacement of Chalcone-Ethers with Chalcone-Thioethers as Potent and Highly Selective Monoamine Oxidase-B Inhibitors and Their Protein-Ligand Interactions.

Mathew B, Oh JM, Khames A, Abdelgawad MA, Rangarajan TM, Nath LR, Agoni C, Soliman MES, Mathew GE, Kim H. Mathew B, et al. Among authors: rangarajan tm. Pharmaceuticals (Basel). 2021 Nov 11;14(11):1148. doi: 10.3390/ph14111148. Pharmaceuticals (Basel). 2021. PMID: 34832930 Free PMC article.

8

Revealing the role of the benzyloxy pharmacophore in the design of a new class of monoamine oxidase-B inhibitors.

Sudevan ST, Rangarajan TM, Al-Sehemi AG, Nair AS, Koyiparambath VP, Mathew B. Sudevan ST, et al. Among authors: rangarajan tm. Arch Pharm (Weinheim). 2022 Aug;355(8):e2200084. doi: 10.1002/ardp.202200084. Epub 2022 May 13. Arch Pharm (Weinheim). 2022. PMID: 35567313 Review.

9

Two dimensional-QSAR and molecular dynamics studies of a selected class of aldoxime- and hydroxy-functionalized chalcones as monoamine oxidase-B inhibitors.

Mathew B, Ravichandran V, Raghuraman S, Rangarajan TM, Abdelgawad MA, Ahmad I, Patel HM, Kim H. Mathew B, et al. Among authors: rangarajan tm. J Biomol Struct Dyn. 2023 Nov;41(19):9256-9266. doi: 10.1080/07391102.2022.2146198. Epub 2022 Nov 21. J Biomol Struct Dyn. 2023. PMID: 36411738

10

Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors.

Sudevan ST, Oh JM, Abdelgawad MA, Abourehab MAS, Rangarajan TM, Kumar S, Ahmad I, Patel H, Kim H, Mathew B. Sudevan ST, et al. Among authors: rangarajan tm. Sci Rep. 2022 Dec 27;12(1):22404. doi: 10.1038/s41598-022-26929-x. Sci Rep. 2022. PMID: 36575270 Free PMC article.

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