Qiu H - Search Results

1

Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Therapeutic Antibody Cocktail REGEN-COV Concentrations in COVID-19 Patient Serum.

Zhong X, Nayak S, Guo L, Raidas S, Zhao Y, Weiss R, Andisik M, Elango C, Sumner G, Irvin SC, Partridge MA, Yan H, E SY, Qiu H, Mao Y, Torri A, Li N. Zhong X, et al. Among authors: qiu h. Anal Chem. 2021 Sep 28;93(38):12889-12898. doi: 10.1021/acs.analchem.1c01613. Epub 2021 Aug 31. Anal Chem. 2021. PMID: 34463470

2

Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry.

Xu X, Huang Y, Pan H, Molden R, Qiu H, Daly TJ, Li N. Xu X, et al. Among authors: qiu h. PLoS One. 2019 Oct 16;14(10):e0223899. doi: 10.1371/journal.pone.0223899. eCollection 2019. PLoS One. 2019. PMID: 31618250 Free PMC article.

3

Isotyping and Semi-Quantitation of Monkey Anti-Drug Antibodies by Immunocapture Liquid Chromatography-Mass Spectrometry.

Huang X, Xu X, Partridge MA, Chen J, Koehler-Stec E, Sumner G, Qiu H, Torri A, Li N. Huang X, et al. Among authors: qiu h. AAPS J. 2021 Jan 6;23(1):16. doi: 10.1208/s12248-020-00538-w. AAPS J. 2021. PMID: 33404777 Free PMC article.

4

Toward unbiased identification and comparative quantification of host cell protein impurities by automated iterative LC-MS/MS (HCP-AIMS) for therapeutic protein development.

Huang Y, Molden R, Hu M, Qiu H, Li N. Huang Y, et al. Among authors: qiu h. J Pharm Biomed Anal. 2021 Jun 5;200:114069. doi: 10.1016/j.jpba.2021.114069. Epub 2021 Apr 20. J Pharm Biomed Anal. 2021. PMID: 33901758 Free article.

5

Analytical characterization of DNA and RNA oligonucleotides by hydrophilic interaction liquid chromatography-tandem mass spectrometry.

Huang M, Xu X, Qiu H, Li N. Huang M, et al. Among authors: qiu h. J Chromatogr A. 2021 Jul 5;1648:462184. doi: 10.1016/j.chroma.2021.462184. Epub 2021 Apr 27. J Chromatogr A. 2021. PMID: 33991753 Free article.

6

Characterization of Proteinaceous Particles in Monoclonal Antibody Drug Products Using Mass Spectrometry.

Xu X, Hu Q, Liu D, Qiu H, Shameem M, Li N. Xu X, et al. Among authors: qiu h. J Pharm Sci. 2021 Oct;110(10):3403-3409. doi: 10.1016/j.xphs.2021.06.014. Epub 2021 Jun 15. J Pharm Sci. 2021. PMID: 34139261 Free article.

7

Site-Specific Quantitation of Drug Conjugations on Antibody-Drug Conjugates (ADCs) Using a Protease-Assisted Drug Deconjugation and Linker-like Labeling (PADDLL) Method.

Yang X, Seol H, Lin W, Xu X, Shen B, Qiu H, Li N. Yang X, et al. Among authors: qiu h. Anal Chem. 2021 Jul 13;93(27):9549-9558. doi: 10.1021/acs.analchem.1c01619. Epub 2021 Jul 1. Anal Chem. 2021. PMID: 34196532

8

Host cell protein profiling of commercial therapeutic protein drugs as a benchmark for monoclonal antibody-based therapeutic protein development.

Molden R, Hu M, Yen E S, Saggese D, Reilly J, Mattila J, Qiu H, Chen G, Bak H, Li N. Molden R, et al. Among authors: qiu h. MAbs. 2021 Jan-Dec;13(1):1955811. doi: 10.1080/19420862.2021.1955811. MAbs. 2021. PMID: 34365906 Free PMC article.

9

Deciphering the High Viscosity of a Therapeutic Monoclonal Antibody in High Concentration Formulations by Microdialysis-Hydrogen/Deuterium Exchange Mass Spectrometry.

Xu X, Zhang A, Xu Y, Cao Y, Cale S, Franklin M, Sarangapani P, Ihnat PM, Qiu H, Liu D, Pyles EA, Shameem M, Li N. Xu X, et al. Among authors: qiu h. J Pharm Sci. 2022 May;111(5):1335-1345. doi: 10.1016/j.xphs.2021.12.027. Epub 2022 Jan 7. J Pharm Sci. 2022. PMID: 34999091

10

Development of a Two-Dimensional Liquid Chromatography-Mass Spectrometry Platform for Simultaneous Multi-Attribute Characterization of Adeno-Associated Viruses.

Wu Z, Wang H, Tustian A, Qiu H, Li N. Wu Z, et al. Among authors: qiu h. Anal Chem. 2022 Feb 22;94(7):3219-3226. doi: 10.1021/acs.analchem.1c04873. Epub 2022 Feb 10. Anal Chem. 2022. PMID: 35142492 Free article.

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