Nicolaes GAF - Search Results

1

Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity.

Ercig B, Arfman T, Hrdinova J, Wichapong K, Reutelingsperger CPM, Vanhoorelbeke K, Nicolaes GAF, Voorberg J. Ercig B, et al. Among authors: nicolaes gaf. J Biol Chem. 2021 Oct;297(4):101132. doi: 10.1016/j.jbc.2021.101132. Epub 2021 Aug 27. J Biol Chem. 2021. PMID: 34461090 Free PMC article. Review.

2

The role of thrombin exosites I and II in the activation of human coagulation factor V.

Segers K, Dahlbäck B, Bock PE, Tans G, Rosing J, Nicolaes GA. Segers K, et al. J Biol Chem. 2007 Nov 23;282(47):33915-24. doi: 10.1074/jbc.M701123200. Epub 2007 Sep 18. J Biol Chem. 2007. PMID: 17878169 Free PMC article.

3

Identification of surface epitopes of human coagulation factor Va that are important for interaction with activated protein C and heparin.

Segers K, Dahlbäck B, Rosing J, Nicolaes GA. Segers K, et al. J Biol Chem. 2008 Aug 15;283(33):22573-81. doi: 10.1074/jbc.M801724200. Epub 2008 Jun 2. J Biol Chem. 2008. PMID: 18519572 Free article.

4

Engineered annexin A5 variants have impaired cell entry for molecular imaging of apoptosis using pretargeting strategies.

Ungethüm L, Kenis H, Nicolaes GA, Autin L, Stoilova-McPhie S, Reutelingsperger CP. Ungethüm L, et al. J Biol Chem. 2011 Jan 21;286(3):1903-10. doi: 10.1074/jbc.M110.163527. Epub 2010 Nov 15. J Biol Chem. 2011. PMID: 21078669 Free PMC article.

5

Optimization of compound ranking for structure-based virtual ligand screening using an established FRED-Surflex consensus approach.

Du J, Bleylevens IW, Bitorina AV, Wichapong K, Nicolaes GA. Du J, et al. Chem Biol Drug Des. 2014 Jan;83(1):37-51. doi: 10.1111/cbdd.12202. Epub 2013 Oct 4. Chem Biol Drug Des. 2014. PMID: 23941463

6

Rational design of small molecules targeting the C2 domain of coagulation factor VIII.

Nicolaes GA, Kulharia M, Voorberg J, Kaijen PH, Wroblewska A, Wielders S, Schrijver R, Sperandio O, Villoutreix BO. Nicolaes GA, et al. Blood. 2014 Jan 2;123(1):113-20. doi: 10.1182/blood-2013-05-503227. Epub 2013 Nov 13. Blood. 2014. PMID: 24227818 Free article.

7

Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis.

Wildhagen KC, García de Frutos P, Reutelingsperger CP, Schrijver R, Aresté C, Ortega-Gómez A, Deckers NM, Hemker HC, Soehnlein O, Nicolaes GA. Wildhagen KC, et al. Blood. 2014 Feb 13;123(7):1098-101. doi: 10.1182/blood-2013-07-514984. Epub 2013 Nov 21. Blood. 2014. PMID: 24264231 Free article.

8

Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis.

Wildhagen KC, Schrijver R, Beckers L, ten Cate H, Reutelingsperger CP, Lutgens E, Nicolaes GA. Wildhagen KC, et al. PLoS One. 2014 Jul 17;9(7):e101446. doi: 10.1371/journal.pone.0101446. eCollection 2014. PLoS One. 2014. PMID: 25032959 Free PMC article.

9

Molecular simulation studies of human coagulation factor VIII C domain-mediated membrane binding.

Du J, Wichapong K, Hackeng KM, Nicolaes GA. Du J, et al. Thromb Haemost. 2015 Feb;113(2):373-84. doi: 10.1160/TH14-02-0180. Epub 2014 Oct 30. Thromb Haemost. 2015. PMID: 25354705

10

Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients.

Wildhagen KC, Wiewel MA, Schultz MJ, Horn J, Schrijver R, Reutelingsperger CP, van der Poll T, Nicolaes GA. Wildhagen KC, et al. Thromb Res. 2015 Sep;136(3):542-7. doi: 10.1016/j.thromres.2015.06.035. Epub 2015 Jul 23. Thromb Res. 2015. PMID: 26232351

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