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Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia.
Prieto C, Nguyen DTT, Liu Z, Wheat J, Perez A, Gourkanti S, Chou T, Barin E, Velleca A, Rohwetter T, Chow A, Taggart J, Savino AM, Hoskova K, Dhodapkar M, Schurer A, Barlowe TS, Vu LP, Leslie C, Steidl U, Rabadan R, Kharas MG. Prieto C, et al. Among authors: rabadan r. Nat Cancer. 2021 Jul;2:741-757. doi: 10.1038/s43018-021-00220-w. Epub 2021 Jul 5. Nat Cancer. 2021. PMID: 34458856 Free PMC article.
Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts.
Kode A, Manavalan JS, Mosialou I, Bhagat G, Rathinam CV, Luo N, Khiabanian H, Lee A, Murty VV, Friedman R, Brum A, Park D, Galili N, Mukherjee S, Teruya-Feldstein J, Raza A, Rabadan R, Berman E, Kousteni S. Kode A, et al. Among authors: rabadan r. Nature. 2014 Feb 13;506(7487):240-4. doi: 10.1038/nature12883. Epub 2014 Jan 15. Nature. 2014. PMID: 24429522 Free PMC article.
A Case of T-cell Acute Lymphoblastic Leukemia Relapsed As Myeloid Acute Leukemia.
Paganin M, Buldini B, Germano G, Seganfreddo E, Meglio Ad, Magrin E, Grillo F, Pigazzi M, Rizzari C, Cazzaniga G, Khiabanian H, Palomero T, Rabadan R, Ferrando AA, Basso G. Paganin M, et al. Among authors: rabadan r. Pediatr Blood Cancer. 2016 Sep;63(9):1660-3. doi: 10.1002/pbc.26054. Epub 2016 May 3. Pediatr Blood Cancer. 2016. PMID: 27149388
The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
Varano G, Raffel S, Sormani M, Zanardi F, Lonardi S, Zasada C, Perucho L, Petrocelli V, Haake A, Lee AK, Bugatti M, Paul U, Van Anken E, Pasqualucci L, Rabadan R, Siebert R, Kempa S, Ponzoni M, Facchetti F, Rajewsky K, Casola S. Varano G, et al. Among authors: rabadan r. Nature. 2017 Jun 8;546(7657):302-306. doi: 10.1038/nature22353. Epub 2017 May 31. Nature. 2017. PMID: 28562582
Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization.
Liu Z, Yoshimi A, Wang J, Cho H, Chun-Wei Lee S, Ki M, Bitner L, Chu T, Shah H, Liu B, Mato AR, Ruvolo P, Fabbri G, Pasqualucci L, Abdel-Wahab O, Rabadan R. Liu Z, et al. Among authors: rabadan r. Cancer Discov. 2020 Jun;10(6):806-821. doi: 10.1158/2159-8290.CD-19-1330. Epub 2020 Mar 18. Cancer Discov. 2020. PMID: 32188705 Free PMC article.
The UVSSA complex alleviates MYC-driven transcription stress.
Sato M, Liebau RC, Liu Z, Liu L, Rabadan R, Gautier J. Sato M, et al. Among authors: rabadan r. J Cell Biol. 2021 Feb 1;220(2):e201807163. doi: 10.1083/jcb.201807163. J Cell Biol. 2021. PMID: 33404608 Free PMC article.
Computing the Role of Alternative Splicing in Cancer.
Liu Z, Rabadan R. Liu Z, et al. Among authors: rabadan r. Trends Cancer. 2021 Apr;7(4):347-358. doi: 10.1016/j.trecan.2020.12.015. Epub 2021 Jan 23. Trends Cancer. 2021. PMID: 33500226 Free PMC article. Review.
241 results