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Species selection for nonclinical safety assessment of drug candidates: Examples of current industry practice.
Namdari R, Jones K, Chuang SS, Van Cruchten S, Dincer Z, Downes N, Mikkelsen LF, Harding J, Jäckel S, Jacobsen B, Kinyamu-Akunda J, Lortie A, Mhedhbi S, Mohr S, Schmitt MW, Prior H. Namdari R, et al. Among authors: harding j. Regul Toxicol Pharmacol. 2021 Nov;126:105029. doi: 10.1016/j.yrtph.2021.105029. Epub 2021 Aug 27. Regul Toxicol Pharmacol. 2021. PMID: 34455009 Free article.
The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.
Zabka TS, Burkhardt J, Reagan WJ, Gautier JC, Glaab WE, Guffroy M, Harding J, Brees D, McDuffie E, Ramaiah L, Schultze AE, Smith JD, Wolfreys A, Dalmas DA. Zabka TS, et al. Among authors: harding j. Regul Toxicol Pharmacol. 2021 Mar;120:104857. doi: 10.1016/j.yrtph.2020.104857. Epub 2020 Dec 31. Regul Toxicol Pharmacol. 2021. PMID: 33387566 Free article.
Opportunities and challenges for use of minipigs in nonclinical pharmaceutical development: Results of a follow-up IQ DruSafe survey.
Clarke DO, Datta K, French K, Leach MW, Olaharski D, Mohr S, Strein D, Bussiere J, Feyen B, Gauthier BE, Graziano M, Harding J, Hershman K, Jacob B, Ji S, Lange R, Salian-Mehta S, Sayers B, Thomas N, Flandre T. Clarke DO, et al. Among authors: harding j. Regul Toxicol Pharmacol. 2024 Dec;154:105729. doi: 10.1016/j.yrtph.2024.105729. Epub 2024 Oct 30. Regul Toxicol Pharmacol. 2024. PMID: 39481797 Free article.
ASO Visual Abstract: Adjuvant Cytotoxic Chemotherapy May Not Be Associated with a Survival Advantage for Resected Intrahepatic Cholangiocarcinoma.
Sharib J, Rhodin KE, Liu A, McIntyre S, Bartholomew A, Masoud S, DeLaura I, Kemeny NE, Cercek A, Harding JJ, O'Reilly EM, Abou-Alfa GK, Reidy-Lagunes D, Connell LC, El Dika I, Balachandran VP, Drebin J, Soares KC, Wei AC, Kingham TP, D'Angelica MI, Uronis H, Strickler J, Hsu SD, Morse M, Zani S, Allen PJ, Jarnagin WR, Lidsky ME. Sharib J, et al. Among authors: harding jj. Ann Surg Oncol. 2025 Jan 28. doi: 10.1245/s10434-025-16881-1. Online ahead of print. Ann Surg Oncol. 2025. PMID: 39873846 No abstract available.
Neonatal Nutrition and Brain Structure at 7 Years in Children Born Very Preterm.
Poppe T, Tottman AC, Gamble GD, Jiang Y, Silva AE, Nguyen L, Harding JE, Alsweiler JM, Thompson B; PIANO study group. Poppe T, et al. Among authors: harding je. JAMA Netw Open. 2025 Jan 2;8(1):e2456080. doi: 10.1001/jamanetworkopen.2024.56080. JAMA Netw Open. 2025. PMID: 39853980 Free PMC article.
TP53 Mutation Predicts Worse Survival and Earlier Local Progression in Patients with Hepatocellular Carcinoma Treated with Transarterial Embolization.
Zhao K, Karimi A, Kelly L, Petre E, Marinelli B, Alexander ES, Sotirchos VS, Erinjeri JP, Covey A, Sofocleous CT, Harding JJ, Jarnagin W, Sigel C, Vakiani E, Ziv E, Yarmohammadi H. Zhao K, et al. Among authors: harding jj. Curr Oncol. 2025 Jan 18;32(1):51. doi: 10.3390/curroncol32010051. Curr Oncol. 2025. PMID: 39851967 Free PMC article.
1,769 results