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Page 1
Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model.
Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD. Yang T, et al. Among authors: horscroft n. J Hepatol. 2021 Dec;75(6):1420-1433. doi: 10.1016/j.jhep.2021.08.011. Epub 2021 Aug 25. J Hepatol. 2021. PMID: 34453962 Free article.
mRNA as a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5.
Hauser S, Poenisch M, Schelling Y, Höflinger P, Schuster S, Teegler A, Betten R, Gustafsson JÅ, Hübener-Schmid J, Schlake T, Chevessier-Tünnesen F, Horscroft N, Björkhem I, Schöls L. Hauser S, et al. Among authors: horscroft n. Mol Ther Methods Clin Dev. 2019 Oct 31;15:359-370. doi: 10.1016/j.omtm.2019.10.011. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31828178 Free PMC article.
Corrigendum to 'Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model' [J Hepatol (2021) 1420-1433].
Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD. Yang T, et al. Among authors: horscroft n. J Hepatol. 2022 Jul;77(1):270. doi: 10.1016/j.jhep.2022.03.023. Epub 2022 Apr 7. J Hepatol. 2022. PMID: 35397937 No abstract available.
mRNA-based therapy proves superior to the standard of care for treating hereditary tyrosinemia 1 in a mouse model.
Cacicedo ML, Weinl-Tenbruck C, Frank D, Wirsching S, Straub BK, Hauke J, Okun JG, Horscroft N, Hennermann JB, Zepp F, Chevessier-Tünnesen F, Gehring S. Cacicedo ML, et al. Among authors: horscroft n. Mol Ther Methods Clin Dev. 2022 Jul 15;26:294-308. doi: 10.1016/j.omtm.2022.07.006. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 35949297 Free PMC article.
mRNA mediates passive vaccination against infectious agents, toxins, and tumors.
Thran M, Mukherjee J, Pönisch M, Fiedler K, Thess A, Mui BL, Hope MJ, Tam YK, Horscroft N, Heidenreich R, Fotin-Mleczek M, Shoemaker CB, Schlake T. Thran M, et al. Among authors: horscroft n. EMBO Mol Med. 2017 Oct;9(10):1434-1447. doi: 10.15252/emmm.201707678. EMBO Mol Med. 2017. PMID: 28794134 Free PMC article.
Phenylalanine hydroxylase mRNA rescues the phenylketonuria phenotype in mice.
Cacicedo ML, Weinl-Tenbruck C, Frank D, Limeres MJ, Wirsching S, Hilbert K, Pasha Famian MA, Horscroft N, Hennermann JB, Zepp F, Chevessier-Tünnesen F, Gehring S. Cacicedo ML, et al. Among authors: horscroft n. Front Bioeng Biotechnol. 2022 Oct 7;10:993298. doi: 10.3389/fbioe.2022.993298. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 36277393 Free PMC article.
Preclinical studies of PF-04849285, an interferon-α8 fusion protein for the treatment of HCV.
Flores MV, Hickling TP, Sreckovic S, Fidock MD, Horscroft N, Katragadda M, Savic B, Rawal J, Delpuech-Adams OE, Robas N, Corey T, Nelms L, Lawton M, Marcek J, Stubbs M, Westby M, Ciaramella G. Flores MV, et al. Among authors: horscroft n. Antivir Ther. 2012;17(5):869-81. doi: 10.3851/IMP2099. Epub 2012 Apr 13. Antivir Ther. 2012. PMID: 22505586
27 results