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214 results

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Page 1
Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control.
Ingemarsdotter CK, Tookman LA, Browne A, Pirlo K, Cutts R, Chelela C, Khurrum KF, Leung EY, Dowson S, Webber L, Khan I, Ennis D, Syed N, Crook TR, Brenton JD, Lockley M, McNeish IA. Ingemarsdotter CK, et al. Among authors: mcneish ia. Mol Oncol. 2015 Apr;9(4):791-805. doi: 10.1016/j.molonc.2014.12.007. Epub 2014 Dec 29. Mol Oncol. 2015. PMID: 25560085 Free PMC article.
CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.
Walton J, Blagih J, Ennis D, Leung E, Dowson S, Farquharson M, Tookman LA, Orange C, Athineos D, Mason S, Stevenson D, Blyth K, Strathdee D, Balkwill FR, Vousden K, Lockley M, McNeish IA. Walton J, et al. Among authors: mcneish ia. Cancer Res. 2016 Oct 15;76(20):6118-6129. doi: 10.1158/0008-5472.CAN-16-1272. Epub 2016 Aug 16. Cancer Res. 2016. PMID: 27530326 Free PMC article.
RIPK3 promotes adenovirus type 5 activity.
Weigert M, Binks A, Dowson S, Leung EYL, Athineos D, Yu X, Mullin M, Walton JB, Orange C, Ennis D, Blyth K, Tait SWG, McNeish IA. Weigert M, et al. Among authors: mcneish ia. Cell Death Dis. 2017 Dec 13;8(12):3206. doi: 10.1038/s41419-017-0110-8. Cell Death Dis. 2017. PMID: 29238045 Free PMC article.
NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer.
Leung EYL, Ennis DP, Kennedy PR, Hansell C, Dowson S, Farquharson M, Spiliopoulou P, Nautiyal J, McNamara S, Carlin LM, Fisher K, Davis DM, Graham G, McNeish IA. Leung EYL, et al. Among authors: mcneish ia. Mol Ther Oncolytics. 2020 Feb 15;16:289-301. doi: 10.1016/j.omto.2020.02.001. eCollection 2020 Mar 27. Mol Ther Oncolytics. 2020. PMID: 32195317 Free PMC article.
SMARCA4 regulates the NK-mediated killing of senescent cells.
Reen V, D'Ambrosio M, Søgaard PP, Tyson K, Leeke BJ, Clément I, Dye ICA, Pombo J, Kuba A, Lan Y, Burr J, Bomann IC, Kalyva M, Birch J, Khadayate S, Young G, Provencher D, Mes-Masson AM, Vernia S, McGranahan N, Brady HJM, Rodier F, Nativio R, Percharde M, McNeish IA, Gil J. Reen V, et al. Among authors: mcneish ia. Sci Adv. 2025 Jan 17;11(3):eadn2811. doi: 10.1126/sciadv.adn2811. Epub 2025 Jan 15. Sci Adv. 2025. PMID: 39813356 Free PMC article.
A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor.
Hu JC, Coffin RS, Davis CJ, Graham NJ, Groves N, Guest PJ, Harrington KJ, James ND, Love CA, McNeish I, Medley LC, Michael A, Nutting CM, Pandha HS, Shorrock CA, Simpson J, Steiner J, Steven NM, Wright D, Coombes RC. Hu JC, et al. Clin Cancer Res. 2006 Nov 15;12(22):6737-47. doi: 10.1158/1078-0432.CCR-06-0759. Clin Cancer Res. 2006. PMID: 17121894 Clinical Trial.
214 results